Bile acids are soluble derivatives of cholesterol produced in the liver that subsequently
undergo bacterial transformation yielding a diverse array of metabolites. The bulk of bile …

Bile acids are a large family of atypical steroids which exert their functions by binding to a
family of ubiquitous cell membrane and nuclear receptors. There are two main bile acid …

Bile acids are a group of chemically different steroids generated at the host/microbial
interface. Indeed, while primary bile acids are the end-product of cholesterol breakdown in …

The gastrointestinal tract hosts the largest ecosystem of microorganisms in the body. The
metabolism of ingested nutrients by gut bacteria produces novel chemical mediators that …

Bile acids (BA) are amphipathic steroid acids synthesized from cholesterol in the liver. They
act as detergents to expedite the digestion and absorption of dietary lipids and lipophilic …

Once known exclusively for their role in nutrients absorption, bile acids have emerged as
signaling molecules, generated from cholesterol breakdown, acting on several immune cells …

Bile acids (BAs) are produced from cholesterol in the liver and are termed primary BAs.
Primary BAs are conjugated with glycine and taurine in the liver and then released into the …

Although post-cholecystectomy (PC) patients usually have gastrointestinal complications
and a higher risk of colorectal cancer, previous studies undetected a heightened risk of …

Bile acids, once considered mere dietary surfactants, now emerge as critical modulators of
macronutrient (lipid, carbohydrate, protein) metabolism and the systemic pro …

Non-alcoholic steatosis (NAFLD) and steatohepatitis (NASH) are two highly prevalent
human disorders for which therapy remains suboptimal. Bile acids play an essential role in …