[HTML][HTML] Single-cell transcriptome profiling reveals β cell maturation in stem cell-derived islets after transplantation

P Augsornworawat, KG Maxwell, L Velazco-Cruz… - Cell reports, 2020 - cell.com
Human pluripotent stem cells differentiated to insulin-secreting β cells (SC-β cells) in islet
organoids could provide an unlimited cell source for diabetes cell replacement therapy …

Dysfunction of an anaphase-promoting complex subunit 8 homolog leads to super-short petioles and enlarged petiole angles in soybean

Y Gao, J Zhu, H Zhai, K Xu, X Zhu, H Wu… - International Journal of …, 2023 - mdpi.com
Plant height, petiole length, and the angle of the leaf petiole and branch angles are crucial
traits determining plant architecture and yield in soybean (Glycine max L.). Here, we …

HPD degradation regulated by the TTC36-STK33-PELI1 signaling axis induces tyrosinemia and neurological damage

Y Xie, X Lv, D Ni, J Liu, Y Hu, Y Liu, Y Liu, R Liu… - Nature …, 2019 - nature.com
Decreased expression of 4-hydroxyphenylpyruvic acid dioxygenase (HPD), a key enzyme
for tyrosine metabolism, is a cause of human tyrosinemia. However, the regulation of HPD …

Genetic resistance to DEHP-induced transgenerational endocrine disruption

L Stenz, R Rahban, J Prados, S Nef… - PLoS …, 2019 - journals.plos.org
Di (2-ethylhexyl) phthalate (DEHP) interferes with sex hormones signaling pathways (SHP).
C57BL/6J mice prenatally exposed to 300 mg/kg/day DEHP develop a testicular dysgenesis …

[HTML][HTML] TTC36 inactivation induce malignant properties via Wnt-β-catenin pathway in gastric carcinoma

L Song, X Guo, F Zhao, W Wang, Z Zhao, L Jin… - Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: Tetratricopeptide repeat (TRP)-mediated cofactor proteins are involved in a wide
range of cancers. TTC36 is little studied member of TRP subfamily. This study aimed to …

Proteomic analysis of tear film obtained from diabetic dogs

D Winiarczyk, M Winiarczyk, S Winiarczyk, K Michalak… - Animals, 2020 - mdpi.com
Simple Summary Canine diabetes is a serious disease, which can lead to severe
complications, eventually even death. Currently, all the diagnostic procedures are the …

[HTML][HTML] Tetratricopeptide repeat domain 36 deficiency mitigates renal tubular injury by inhibiting TGF-β1-induced epithelial–mesenchymal transition in a mouse …

X Yan, R Peng, Y Ni, L Chen, Q He, Q Li, Q Zhou - Genes & Diseases, 2022 - Elsevier
The damage of proximal tubular epithelial cells (PTECs) is considered a central event in the
pathogenesis of chronic kidney disease (CKD) and deregulated repair processes of PTECs …

Heat shock-binding protein 21 regulates the innate immune response to viral infection

Y Xu, Q Yang, B Xue, X Wang, R Tian, R Deng… - Journal of …, 2022 - Am Soc Microbiol
The induction of interferons (IFNs) plays an important role in the elimination of invading
pathogens. Heat shock binding protein 21 (HBP21), first known as a molecular chaperone of …

Comparative proteomics analysis of the head proteins of worker honey bees (Apis mellifera) in production stage of royal jelly

R Andyshe, J Nazemi-Rafie, M Maleki… - Journal of Apicultural …, 2024 - Taylor & Francis
Honey bees can be evaluated to study their economic, developmental and immunity
aspects. Apis mellifera has important organs such as the hypopharyngeal gland, mandibular …

Explainable machine learning model identified potential biomarkers in liver cancer survival prediction

Q Pan, AH Hounye, K Miao, L Su, J Wang… - … Signal Processing and …, 2024 - Elsevier
Objective Liver cancer is a malignant tumor with a high incidence, and common treatments
include surgical resection, ablation, arterial catheterization, and liver transplantation …