The endocannabinoid system (ECS) has been shown to be of great importance in the
regulation of numerous physiological and pathological processes. To date, two Class A G …

Thirty years ago, the discovery of a cannabinoid (CB) receptor that interacts with the
psychoactive compound in Cannabis led to the identification of anandamide, an …

Background Recent approved medicines whose active principles are Δ 9
Tetrahidrocannabinol (Δ 9-THC) and/or cannabidiol (CBD) open novel perspectives for …

Accumulating evidence suggests that inflammation plays an important role in the
pathophysiology of the initiation and progression of cardiovascular and metabolic diseases …

Cannabinoids are lipid messengers that modulate a variety of physiological processes and
modify the generation of specific behaviors. In this regard, the cannabinoid receptor type 1 …

Epilepsy contributes to approximately 1% of the global disease burden. By affecting
especially young children as well as older persons of all social and racial variety, epilepsy is …

We investigated the influence of cannabidiol (CBD) on blood pressure (BP) and heart rate
(HR) in spontaneously (SHR) and deoxycorticosterone (DOCA-salt) hypertensive rats …

Abstract Originating from Eastern Asia, the plant Cannabis sativa has been used for
centuries as a medicinal treatment. The unwanted psychotropic effects of one of its major …

Over the last 25 years, the human endocannabinoid system (ECS) has come into the
limelight as an imperative neuro-modulatory system. It is mainly comprised of endogenous …

The search for cannabinoid receptors other than CB1R and CB2R has been ongoing for
over a decade. A number of orphan receptors have been proposed as potential cannabinoid …