Dynamic contrast enhanced MRI (DCE-MRI) enables the quantitative assessment of tumor
status and has found application in both pre-clinical tumor models as well as clinical …

Over the last few decades there has been considerable research into quantifying the
cerebral microvasculature with imaging, for use in studies of the human brain and various …

Before meaningful conclusions can be drawn from clinical measures of cerebral blood
perfusion, the precision of the measurement must be determined and set in the context of …

Purpose To present a novel MR pulse sequence and modeling algorithm to quantify the
water exchange rate (kw) across the blood–brain barrier (BBB) without contrast, and to …

Purpose To compare the test–retest reproducibility of three variants of arterial spin labeling
(ASL): pseudo‐continuous (pCASL), pulsed (PASL) and continuous (CASL). Materials and …

Objective Summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and highlight the latest bench-to-bedside developments. Methods …

Glucocorticoids (GCs) are secreted in an ultradian, pulsatile pattern that emerges from
delays in the feedforward-feedback interaction between the anterior pituitary and adrenal …

The two most common methods for measuring perfusion with MRI are based on dynamic
susceptibility contrast (DSC) and arterial spin labeling (ASL). Although clinical experience to …

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) can assess tumor
perfusion, microvascular vessel wall permeability and extravascular–extracellular volume …

Arterial spin labeling is a magnetic resonance method for the measurement of cerebral
blood flow. In its simplest form, the perfusion contrast in the images gathered by this …