Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

Cerebral blood flow (CBF) and its distribution are highly sensitive to changes in the partial
pressure of arterial CO2 (PaCO2). This physiological response, termed cerebrovascular …

This study investigated the effects of air temperature and ventilation on the sleep quality of
elderly subjects and elucidated the mechanisms involved. Sixteen subjects aged over 65 …

The respiratory system is a complex interplay between the central nervous system,
respiratoryrelated motor neurons, and the muscles of respiration. During wakefulness, both …

Substantial advances have been made recently into the discovery of fundamental
mechanisms underlying the neural control of breathing and even some inroads into …

Humans emit carbon dioxide (CO 2) as a product of their metabolism. No measurements of
CO 2 emission rates (CERs) of elderly sleeping people have yet been reported. This study …

Background: Whether loss of wakefulness itself can influence pharyngeal dilator muscle
activity and responsiveness is currently unknown. A study was therefore undertaken to …

In patients with obstructive sleep apnea (OSA), substantial increases in genioglossus (GG)
activity during hypopneas/apneas usually fail to restore normal airflow. We have previously …

Surgical patients should be screened for OSA and patients with OSA should continue using
positive airway pressure devices postoperatively. Use of shorter acting and less sedating …

After introducing the respiratory control system, a previously developed model of the
respiratory chemoreflexes, based on rebreathing test data, is briefly described. This model is …