A limbic brain area, the amygdala plays a key role in emotional responses and affective
states and disorders such as learned fear, anxiety, and depression. The amygdala has also …

Background Calcitonin gene-related peptide (CGRP) is widely distributed in nociceptive
pathways in human peripheral and central nervous system and its receptors are also …

The cellular and molecular mechanisms mediating histamine-independent itch in primary
sensory neurons are largely unknown. Itch induced by chloroquine (CQ) is a common side …

Neuropeptides play important modulatory roles throughout the nervous system, functioning
as direct effectors or as interacting partners with other neuropeptide and neurotransmitter …

The balance between T helper type 1 (TH1) cells and other TH cells is critical for antiviral
and anti-tumour responses,–, but how this balance is achieved remains poorly understood …

Calcitonin gene‐related peptide (CGRP) is a key mediator in primary headaches including
migraine. Animal models of meningeal nociception demonstrate both peripheral and central …

Over the past two decades, a convergence of basic and clinical evidence has established
the neuropeptide calcitonin-gene-related peptide (CGRP) as a key player in migraine …

Migraine is a highly prevalent neurovascular disorder that can be provoked by infusion of
calcitonin gene-related peptide (CGRP). CGRP, a neuropeptide released from activated …

Peptides released in the spinal cord from the central terminals of nociceptors contribute to
the persistent hyperalgesia that defines the clinical experience of chronic pain. Using …

The neuropeptide calcitonin gene-related peptide (CGRP) from the trigeminal ganglion has
been established as a key player in the pathogenesis of migraine. In this study, we provide …