Recent advances in capillary electrophoresis‐mass spectrometry: Instrumentation, methodology and applications

A Stolz, K Jooß, O Höcker, J Römer, J Schlecht… - …, 2019 - Wiley Online Library
Capillary electrophoresis (CE) offers fast and high‐resolution separation of charged
analytes from small injection volumes. Coupled to mass spectrometry (MS), it represents a …

CE‐MS for metabolomics: Developments and applications in the period 2018–2020

W Zhang, R Ramautar - Electrophoresis, 2021 - Wiley Online Library
Capillary electrophoresis‐mass spectrometry (CE‐MS) is now a mature analytical technique
in metabolomics, notably for the efficient profiling of polar and charged metabolites. Over the …

Capillary electrophoresis-mass spectrometry at trial by metabo-ring: effective electrophoretic mobility for reproducible and robust compound annotation

N Drouin, M Van Mever, W Zhang, E Tobolkina… - Analytical …, 2020 - ACS Publications
Capillary zone electrophoresis-mass spectrometry (CE-MS) is a mature analytical tool for the
efficient profiling of (highly) polar and ionizable compounds. However, the use of CE-MS in …

The maternal serum metabolome by multisegment injection-capillary electrophoresis-mass spectrometry: a high-throughput platform and standardized data workflow …

M Shanmuganathan, Z Kroezen, B Gill, S Azab… - Nature …, 2021 - nature.com
A standardized data workflow is described for large-scale serum metabolomic studies using
multisegment injection-capillary electrophoresis-mass spectrometry. Multiplexed …

CE‐MS for metabolomics: Developments and applications in the period 2016–2018

R Ramautar, GW Somsen, GJ de Jong - Electrophoresis, 2019 - Wiley Online Library
In the field of metabolomics, CE‐MS is now recognized as a strong analytical technique for
the analysis of (highly) polar and charged metabolites in a wide range of biological samples …

Reliability of plasma polar metabolite concentrations in a large-scale cohort study using capillary electrophoresis-mass spectrometry

S Harada, A Hirayama, Q Chan, A Kurihara, K Fukai… - PloS one, 2018 - journals.plos.org
Background Cohort studies with metabolomics data are becoming more widespread,
however, large-scale studies involving 10,000 s of participants are still limited, especially in …

ROMANCE: A new software tool to improve data robustness and feature identification in CE‐MS metabolomics

V González‐Ruiz, Y Gagnebin, N Drouin… - …, 2018 - Wiley Online Library
The use of capillary electrophoresis coupled to mass spectrometry (CE‐MS) in
metabolomics remains an oddity compared to the widely adopted use of liquid …

Challenges in analysis of hydrophilic metabolites using chromatography coupled with mass spectrometry

Q Hu, H Tang, Y Wang - Journal of Analysis and Testing, 2020 - Springer
Hydrophilic metabolites play important roles in cellular energy metabolism, signal
transduction, immunity. However, there are challenges in both identification and …

[PDF][PDF] Analytical techniques used in metabolomics: A review

Y Munjal, RK Tonk, R Sharma - Systematic Reviews in Pharmacy, 2022 - researchgate.net
Metabolomics is a branch of chemistry in which endogenous metabolites present in a
biological sample are accessed and efforts are made for their identification as well as …

Metabolomics in chronic kidney disease: Strategies for extended metabolome coverage

Y Gagnebin, B Julien, P Belén, R Serge - Journal of pharmaceutical and …, 2018 - Elsevier
Chronic kidney disease (CKD) is becoming a major public health issue as prevalence is
increasing worldwide. It also represents a major challenge for the identification of new early …