In the 1970s, treatment with thyroid extract was superseded by levothyroxine, a synthetic l
form of tetraiodothyronine. Since then, no major innovation has emerged for the treatment of …

Background: Fourteen clinical trials have not shown a consistent benefit of combination
therapy with levothyroxine (LT4) and liothyronine (LT3). Despite the publication of these …

Objective Dissatisfaction with treatment and impaired quality of life (QOL) are reported
among people with treated hypothyroidism. We aimed to gain insight into this. Design and …

Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed.
Despite the basic tenets of initiating and adjusting levothyroxine being agreed on, there are …

A significant minority of patients with hypothyroidism report persistent symptoms despite
achieving normal thyroid biochemistry after levothyroxine (L‐T4) replacement. Four principal …

Background: Hypothyroid patients often report dissatisfaction and poor quality of life. This
survey explored the impact of hypothyroidism on patient satisfaction, everyday living …

Background: Combined therapy with levothyroxine (LT4)/L-triiodothyronine (LT3) has
garnered attention among clinicians and patients as a potential treatment alternative to LT4 …

Background: Hypothyroidism is common, however, aspects of its treatment remain
controversial. Our survey aimed at documenting treatment choices of European thyroid …

There are many thyroid-related factors that combine with non-thyroid-related factors in order
to affect the patient response to treatment of hypothyroidism, in terms of their satisfaction with …

Primary hypothyroidism severely impacts the quality of life of patients through a decrease in
the production of the thyroid hormones T3 and T4, leading to symptoms affecting …