Fluorescent analogs of biomolecular building blocks: design, properties, and applications

RW Sinkeldam, NJ Greco, Y Tor - Chemical reviews, 2010 - ACS Publications
Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …

Fundamental photophysics of isomorphic and expanded fluorescent nucleoside analogues

D Dziuba, P Didier, S Ciaco, A Barth… - Chemical Society …, 2021 - pubs.rsc.org
Fluorescent nucleoside analogues (FNAs) are structurally diverse mimics of the natural
essentially non-fluorescent nucleosides which have found numerous applications in probing …

DNA-multichromophore systems

YN Teo, ET Kool - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION: GOALS OF MULTICHROMOPHORE STUDIES Multichromophoric
systems have gained intense interest in recent decades. 1 The arraying of chromophores at …

Fluorescent nucleic acid base analogues

LM Wilhelmsson - Quarterly reviews of biophysics, 2010 - cambridge.org
The use of fluorescent nucleic acid base analogues is becoming increasingly important in
the fields of biology, biochemistry and biophysical chemistry as well as in the field of DNA …

Probing of nucleic acid structures, dynamics, and interactions with environment-sensitive fluorescent labels

BY Michel, D Dziuba, R Benhida… - Frontiers in …, 2020 - frontiersin.org
Fluorescence labeling and probing are fundamental techniques for nucleic acid analysis
and quantification. However, new fluorescent probes and approaches are urgently needed …

Chemical methods for the modification of RNA

M Flamme, LK McKenzie, I Sarac, M Hollenstein - Methods, 2019 - Elsevier
RNA is often considered as being the vector for the transmission of genetic information from
DNA to the protein synthesis machinery. However, besides translation RNA participates in a …

[HTML][HTML] DNA modification under mild conditions by Suzuki–Miyaura cross-coupling for the generation of functional probes

L Lercher, JF McGouran, BM Kessler… - … (International ed. in …, 2013 - ncbi.nlm.nih.gov
The study of DNA, as the carrier of genetic information, is a cornerstone of modern biology.
DNA hybridization determined by complementarity has allowed the design of many DNA …

Microenvironment-sensitive fluorescent nucleotide probes from benzofuran, benzothiophene, and selenophene as substrates for DNA polymerases

P Ghosh, HM Kropp, K Betz, S Ludmann… - Journal of the …, 2022 - ACS Publications
DNA polymerases can process a wide variety of structurally diverse nucleotide substrates,
but the molecular basis by which the analogs are processed is not completely understood …

A survey of chemical methods for sugar-nucleotide synthesis

GK Wagner, T Pesnot, RA Field - Natural product reports, 2009 - pubs.rsc.org
Covering: up to 2009Sugar-nucleotides are essential intermediates in carbohydrate
metabolism and glycoconjugate biosynthesis. Structurally, sugar-nucleotides are composed …

Fluorescent nucleoside analogs: probes for investigating nucleic acid structure and function

AA Tanpure, MG Pawar… - Israel Journal of …, 2013 - Wiley Online Library
Base‐modified fluorescent nucleoside analog probes have been very valuable in the study
of nucleic acid structure and function. Many of them structurally resemble natural bases, and …