Inflammation and its resolution as determinants of acute coronary syndromes

P Libby, I Tabas, G Fredman, EA Fisher - Circulation research, 2014 - Am Heart Assoc
Inflammation contributes to many of the characteristics of plaques implicated in the
pathogenesis of acute coronary syndromes. Moreover, inflammatory pathways not only …

Targeting inflammation in metabolic syndrome

FK Welty, A Alfaddagh, TK Elajami - Translational research, 2016 - Elsevier
The metabolic syndrome (MetS) is comprised of a cluster of closely related risk factors,
including visceral adiposity, insulin resistance, hypertension, high triglyceride, and low high …

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

A Ichimura, A Hirasawa, O Poulain-Godefroy… - Nature, 2012 - nature.com
Free fatty acids provide an important energy source as nutrients, and act as signalling
molecules in various cellular processes,,,. Several G-protein-coupled receptors have been …

Atherosclerosis–a matter of unresolved inflammation

J Viola, O Soehnlein - Seminars in immunology, 2015 - Elsevier
Atherosclerosis is commonly looked upon as a chronic inflammatory disease of the arterial
wall arising from an unbalanced lipid metabolism and a maladaptive inflammatory response …

TLR4 and insulin resistance

JJ Kim, DD Sears - Gastroenterology research and practice, 2010 - Wiley Online Library
Chronic inflammation is a key feature of insulin resistance and obesity. Toll‐Like Receptor 4
(TLR4), involved in modulating innate immunity, is an important mediator of insulin …

Fatty acid regulation of hepatic lipid metabolism

DB Jump - Current Opinion in Clinical Nutrition & Metabolic Care, 2011 - journals.lww.com
Fatty acid regulation of hepatic lipid metabolism : Current Opinion in Clinical Nutrition &
Metabolic Care Fatty acid regulation of hepatic lipid metabolism : Current Opinion in Clinical …

The role of stearoyl‐CoA desaturase in obesity, insulin resistance, and inflammation

H Sampath, JM Ntambi - Annals of the New York Academy of …, 2011 - Wiley Online Library
Stearoyl‐CoA desaturase 1 (SCD1) is an essential lipogenic enzyme that has been shown
to play an intrinsic role in the development of obesity and related conditions, such as insulin …

The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD)

Q Liu, S Bengmark, S Qu - Lipids in health and disease, 2010 - Springer
Nonalcoholic fatty liver disease is increasingly regarded as a hepatic manifestation of
metabolic syndrome, and the severity of nonalcoholic fatty liver disease seems to increase in …

ATP-binding membrane cassette transporter A1 (ABCA1): a possible link between inflammation and reverse cholesterol transport

K Yin, D Liao, C Tang - Molecular medicine, 2010 - Springer
Atherosclerosis is characterized by a chronic inflammatory condition that involves numerous
cellular and molecular inflammatory components. A wide array of inflammatory mediators …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …