Nutrition and frailty: opportunities for prevention and treatment

M Ni Lochlainn, NJ Cox, T Wilson, RPG Hayhoe… - Nutrients, 2021 - mdpi.com
Frailty is a syndrome of growing importance given the global ageing population. While frailty
is a multifactorial process, poor nutritional status is considered a key contributor to its …

[HTML][HTML] Vitamin D and multiple health outcomes: an umbrella review of observational studies, randomized controlled trials, and Mendelian randomization studies

D Liu, X Meng, Q Tian, W Cao, X Fan, L Wu, M Song… - Advances in …, 2022 - Elsevier
Observational studies, randomized controlled trials (RCTs), and Mendelian randomization
(MR) studies have yielded inconsistent results on the associations of vitamin D …

The Asia-Pacific clinical practice guidelines for the management of frailty

E Dent, C Lien, WS Lim, WC Wong, CH Wong… - Journal of the American …, 2017 - Elsevier
Abstract Objective To develop Clinical Practice Guidelines for the screening, assessment
and management of the geriatric condition of frailty. Methods An adapted Grading of …

Prevalence and associated risk factors of cognitive frailty: a systematic review and meta-analysis

T Zhang, Y Ren, P Shen, S Jiang, Y Yang… - Frontiers in Aging …, 2022 - frontiersin.org
Objective Currently, the prevalence of CF (Cognitive Frailty) is not very clear, and the
relationship between CF and its associated risk factors has not been accurately evaluated …

An update on protein, leucine, omega-3 fatty acids, and vitamin D in the prevention and treatment of sarcopenia and functional decline

AJ Tessier, S Chevalier - Nutrients, 2018 - mdpi.com
Aging is associated with sarcopenia and functional decline, leading to frailty and disability.
As a modifiable risk factor, nutrition may represent a target for preventing or postponing the …

[HTML][HTML] Altered immune system in frailty: genetics and diet may influence inflammation

O Pansarasa, C Pistono, A Davin, M Bordoni… - Ageing research …, 2019 - Elsevier
Frailty is a complex geriatric syndrome associated with biological vulnerability to stressors
and decreased physiological reserve. Its etiology and pathogenesis are not completely …

Approaches to the diagnosis and prevention of frailty

SJ Woolford, O Sohan, EM Dennison, C Cooper… - Aging clinical and …, 2020 - Springer
An individual who is living with frailty has impairments in homeostasis across several body
systems and is more vulnerable to stressors that may ultimately predispose them to negative …

The ageing pancreas: a systematic review of the evidence and analysis of the consequences

JM Löhr, N Panic, M Vujasinovic… - Journal of internal …, 2018 - Wiley Online Library
Senior people constitute the fastest growing segment of the population. The elderly are at
risk for malnutrition, thought to be caused by reduced food intake or involution of the …

[HTML][HTML] The impact of frailty on COVID-19 outcomes: a systematic review and meta-analysis of 16 cohort studies

Y Yang, K Luo, Y Jiang, Q Yu, X Huang, J Wang… - The Journal of nutrition …, 2021 - Elsevier
Background Frail patients are increasingly vulnerable to stress, which is mainly manifested
by a reduced physiologic reserve in metabolic and immune systems and neuromuscular …

Low vitamin D levels and frailty status in older adults: a systematic review and meta-analysis

D Marcos-Pérez, M Sánchez-Flores, S Proietti… - Nutrients, 2020 - mdpi.com
Serum vitamin D deficiency is widespread among older adults and is a potential modifiable
risk factor for frailty. Moreover, frailty has been suggested as an intermediate step in the …