Role of inositols and inositol phosphates in energy metabolism

S Chatree, N Thongmaen, K Tantivejkul, C Sitticharoon… - Molecules, 2020 - mdpi.com
Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as
phytic acid or IP6, with their biological activities received much attention for their role in …

TUNEL assay: a powerful tool for kidney injury evaluation

CL Moore, AV Savenka, AG Basnakian - International journal of molecular …, 2021 - mdpi.com
Terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay is a long-
established assay used to detect cell death-associated DNA fragmentation (3'-OH DNA …

Selenium alleviates cadmium-induced mitophagy through FUNDC1-mediated mitochondrial quality control pathway in the lungs of sheep

S Lin, F Yang, M Hu, J Chen, G Chen, A Hu, X Li… - Environmental …, 2023 - Elsevier
Cadmium (Cd) is a poisonous metal element that causes mitochondrial dysfunction.
Selenium (Se) can reduce the damage of Cd to various organs of animals, but the protective …

Cadmium induced cerebral toxicity via modulating MTF1-MTs regulatory axis

M Talukder, SS Bi, HT Jin, J Ge, C Zhang, MW Lv… - Environmental …, 2021 - Elsevier
Metal-responsive transcription factor 1 (MTF1) participates in redox homeostasis and heavy
metals detoxification via regulating the expression of metal responsive genes. However, the …

Grape (Vitis vinifera L.) phytochemicals and their biochemical protective mechanisms against leading pathologies

U Majeed, A Shafi, H Majeed, K Akram, X Liu, J Ye… - Food Chemistry, 2023 - Elsevier
The intake of herbal dietary constituents, mostly fruits and vegetables, have been
considered well-known to prevent pathologies (degenerative diseases). Consumer …

Endocrine disruptors and thyroid autoimmunity

S Benvenga, G Elia, F Ragusa, SR Paparo… - Best Practice & …, 2020 - Elsevier
Many papers evaluated the effect of the environmental, or occupational endocrine disruptors
(ED), on the thyroid gland, that can lead to thyroid autoimmunity. A higher prevalence of …

Inositols depletion and resistance: Principal mechanisms and therapeutic strategies

E Lepore, R Lauretta, M Bianchini… - International Journal of …, 2021 - mdpi.com
Inositols are natural molecules involved in several biochemical and metabolic functions in
different organs and tissues. The term “inositols” refers to five natural stereoisomers, among …

Protective effect of vitamin E on cadmium-induced renal oxidative damage and apoptosis in rats

J Fang, S Xie, Z Chen, F Wang, K Chen, Z Zuo… - Biological trace element …, 2021 - Springer
Cadmium (Cd), a widely distributed heavy metal, is extremely toxic to the kidney. Vitamin E
(VE) is an important antioxidant in the body. It is known that VE exerts a protective effect on …

[HTML][HTML] The preferential accumulation of cadmium ions among various tissues in mice

YT Tai, SH Chou, CY Cheng, CT Ho, HC Lin, SM Jung… - Toxicology reports, 2022 - Elsevier
Cadmium (Cd) is hazardous to human health because of its toxicity and long half-life of
clearance. Many studies have explored the relationship between chronic Cd exposure and …

Glimepiride ameliorates renal toxicity induced by cadmium in mice: Modulation of Jun N terminal kinase (JNK)/nuclear factor kappa B (NF-κB) and phosphatidylinositol …

MK ElMahdy, MO Zaki, AA Al-Karmalawy, W Abdo… - Life Sciences, 2022 - Elsevier
Aims Nephrotoxicity is one of the most serious health consequences of cadmium (Cd) toxic
exposure. Cd was associated with nephrotoxicity through different mechanisms including …