The sympathetic nervous system and blood pressure in humans: implications for hypertension

JP Fisher, JFR Paton - Journal of human hypertension, 2012 - nature.com
A neurogenic component to primary hypertension (hypertension) is now well established.
Along with raised vasomotor tone and increased cardiac output, the chronic activation of the …

Deep brain stimulation for chronic pain

SGJ Boccard, EAC Pereira, TZ Aziz - Journal of Clinical Neuroscience, 2015 - Elsevier
Deep brain stimulation (DBS) is a neurosurgical intervention popularised in movement
disorders such as Parkinson's disease, and also reported to improve symptoms of epilepsy …

Long-term outcomes of deep brain stimulation for neuropathic pain

SGJ Boccard, EAC Pereira, L Moir, TZ Aziz… - Neurosurgery, 2013 - journals.lww.com
BACKGROUND: Deep brain stimulation (DBS) to treat neuropathic pain refractory to
pharmacotherapy has reported variable outcomes and has gained United Kingdom but not …

Mapping the “depression switch” during intraoperative testing of subcallosal cingulate deep brain stimulation

KS Choi, P Riva-Posse, RE Gross… - JAMA neurology, 2015 - jamanetwork.com
Importance The clinical utility of monitoring behavioral changes during intraoperative testing
of subcallosal cingulate deep brain stimulation is unknown. Objective To characterize the …

An autonomic neuroprosthesis: noninvasive electrical spinal cord stimulation restores autonomic cardiovascular function in individuals with spinal cord injury

AA Phillips, JW Squair, DG Sayenko… - Journal of …, 2018 - liebertpub.com
Despite autonomic dysfunction after spinal cord injury (SCI) being the major cause of death
and a top health priority, the clinical management options for these conditions are limited to …

Device therapy of hypertension

F Mahfoud, MP Schlaich, MD Lobo - Circulation research, 2021 - Am Heart Assoc
In the past decade, efforts to improve blood pressure control have looked beyond
conventional approaches of lifestyle modification and drug therapy to embrace …

The current state of deep brain stimulation for chronic pain and its context in other forms of neuromodulation

SM Farrell, A Green, T Aziz - Brain Sciences, 2018 - mdpi.com
Chronic intractable pain is debilitating for those touched, affecting 5% of the population.
Deep brain stimulation (DBS) has fallen out of favour as the centrally implantable …

Dissecting axes of autonomic control in humans: insights from neuroimaging

HD Critchley, Y Nagai, MA Gray, CJ Mathias - Autonomic Neuroscience, 2011 - Elsevier
The combination of functional brain imaging with measurement of peripheral autonomic
responses in humans can provide insight into the embodiment of mental processes and the …

[HTML][HTML] Neuropathic pain and deep brain stimulation

EAC Pereira, TZ Aziz - Neurotherapeutics, 2014 - Elsevier
Deep brain stimulation (DBS) is a neurosurgical intervention the efficacy, safety, and utility of
which are established in the treatment of Parkinson's disease. For the treatment of chronic …

Therapeutic strategies for targeting excessive central sympathetic activation in human hypertension

JP Fisher, PJ Fadel - 2010 - Wiley Online Library
The pathogenesis of hypertension and its mode of progression are complex, multifactoral
and incompletely understood. However, there is accumulating evidence from humans and …