Why do only some individuals develop pathological anxiety following adverse events? Fear acquisition, extinction and return of fear paradigms serve as experimental learning models …
K MacDonald, ML Thomas, AF Sciolla, B Schneider… - PloS one, 2016 - journals.plos.org
Childhood maltreatment has diverse, lifelong impact on morbidity and mortality. The Childhood Trauma Questionnaire (CTQ) is one of the most commonly used scales to assess …
D Scheinost, R Sinha, SN Cross, SH Kwon, G Sze… - Pediatric …, 2017 - nature.com
Human neurodevelopment requires the organization of neural elements into complex structural and functional networks called the connectome. Emerging data suggest that …
Post‐traumatic stress disorder (PTSD) and alcohol‐use disorder (AUD) are highly comorbid in humans. Although we have some understanding of the structural and functional brain …
D Barch, D Pagliaccio, A Belden… - American Journal of …, 2016 - Am Psychiatric Assoc
Objective: In this study, the authors tested the hypothesis that poverty experienced in early childhood, as measured by income-to-needs ratio, has an impact on functional brain …
Using resting‐state functional magnetic resonance imaging, we test the hypothesis that subjects with post‐traumatic stress disorder (PTSD) are characterized by reduced temporal …
RH Kaiser, R Clegg, F Goer, P Pechtel… - Psychological …, 2018 - cambridge.org
BackgroundExposure to threat-related early life stress (ELS) has been related to vulnerability for stress-related disorders in adulthood, putatively via disrupted corticolimbic …
D Rangaprakash, R Tadayonnejad… - Brain imaging and …, 2021 - Springer
The hemodynamic response function (HRF) represents the transfer function linking neural activity with the functional MRI (fMRI) signal, modeling neurovascular coupling. Since HRF is …
Early life stress (ELS) may accelerate frontoamygdala development related to socioemotional processing, serving as a potential source of resilience. Whether this circuit is …