[HTML][HTML] Large-scale neural network computations and multivariate representations during approach-avoidance conflict decision-making

N Moughrabi, C Botsford, TS Gruichich, A Azar… - NeuroImage, 2022 - Elsevier
Many real-world situations require navigating decisions for both reward and threat. While
there has been significant progress in understanding mechanisms of decision-making and …

Neural responding during uncertain threat anticipation in pediatric anxiety

KJ Michalska, B Benson, EJ Ivie, JF Sachs… - International Journal of …, 2023 - Elsevier
Excessive fear responses to uncertain threat are a key feature of anxiety disorders (ADs),
though most mechanistic work considers adults. As ADs onset in childhood and confer risk …

Behavioral and brain reactivity to uncertain stress prospectively predicts binge drinking in youth

SM Gorka, M Radoman, J Jimmy, KA Kreutzer… - …, 2023 - nature.com
Prior studies show that individuals with alcohol use disorder exhibit exaggerated behavioral
and brain reactivity to uncertain threats (U-threat). It is posited this brain-based factor …

A rare scare: The role of intolerance of uncertainty in startle responses and event-related potentials in anticipation of unpredictable threat

HP Carsten, K Härpfer, A Riesel - International Journal of …, 2022 - Elsevier
Intolerance of uncertainty (IU) represents a transdiagnostic risk factor for internalizing
psychopathology. However, little is known regarding its psychophysiological correlates. IU is …

Neural and self-report measures of sensitivity to uncertainty as predictors of COVID-related negative affect

KJ Khorrami, CA Manzler, KA Kreutzer… - Psychiatry Research …, 2022 - Elsevier
The COVID-19 pandemic has been a period of unprecedented uncertainty. Research
indicates individuals differ in their response to uncertainty and these differences are …

Intolerance of uncertainty and functional connectivity of the anterior insula during anticipation of unpredictable reward

M Radoman, SM Gorka - International Journal of Psychophysiology, 2023 - Elsevier
Individuals with high intolerance of uncertainty (IU) tend to display maladaptive cognitive,
behavioral, physiological, and/or neural responses during anticipation of uncertain or …

Altered Effective Connectivity During Threat Anticipation in Individuals With Alcohol Use Disorder

M Radoman, KL Phan, OA Ajilore, SM Gorka - … Cognitive Neuroscience and …, 2024 - Elsevier
Background A developing theory and recent research suggest that heightened reactivity to
uncertain stressors or threats may be an important individual difference factor that facilitates …

[HTML][HTML] Problem drinking and the interaction of reward, negative emotion, and cognitive control circuits during cue-elicited craving

TM Le, Y Chen, S Chaudhary, CSR Li - Addiction Neuroscience, 2022 - Elsevier
Individuals engage in alcohol consumption to seek reward and/or alleviate negative
emotions. The neural processes subserving reward response and negative emotion thus …

Intolerance of uncertainty and cognition in breast cancer survivors: the mediating role of anxiety

Y Yang, SM Gorka, ML Pennell, K Weinhold, T Orchard - Cancers, 2023 - mdpi.com
Simple Summary Approximately 30% of breast cancer survivors experience cancer-related
cognitive impairment (CRCI) after cancer treatments. Given that CRCI adversely affects …

Reward-related neural dysfunction in youth with a history of suicidal ideation: The importance of temporal predictability

SM Gorka, CA Manzler, EE Jones, RJ Smith… - Journal of psychiatric …, 2023 - Elsevier
Abnormal reward processing is an important yet understudied risk factor for suicide. Recent
neuroimaging studies have found that suicidality is associated with abnormal reward-related …