The extracellular matrix is a network of secreted macromolecules that provides a
harmonious meshwork for the growth and homeostatic development of organisms. It …

The extracellular matrix is engaged in an ever-evolving and elegant ballet of dynamic
reciprocity that directly and bi-directionally regulates cell behavior. Homeostatic and …

Background The contribution of the tumor microenvironment and extracellular matrix to the
aggressive biology of Gastric Cancer (GC) has been recently characterized; however, the …

Alterations in extracellular matrix (ECM) components that modulate inflammatory cell
behavior have been shown to serve as early starters for multifactorial diseases such as …

Colon cancer is one of the first tumor types where a functional link between inflammation
and tumor onset has been described; however, the microenvironmental cues affecting colon …

Collective cell behaviour during embryogenesis and tissue repair requires the coordination
of intercellular junctions, cytoskeleton-dependent shape changes controlled by Rho …

Gastric cancer is a frequent human tumor and often a lethal disease. Targeted therapy for
gastric carcinomas is far behind vis-à-vis other solid tumors, primarily because of the paucity …

Lymphatic vessels (LVs) play a pivotal role in the control of tissue homeostasis and also
have emerged as important regulators of immunity, inflammation and tumor metastasis …

Background RNA methylation is a significant form of post-transcriptional modification that
has been implicated in various diseases, including cancers. One prominent type of RNA …

Integrin α4β1 belongs to the leukocyte integrin family and represents a therapeutic target of
relevant interest given its primary role in mediating inflammation, autoimmune pathologies …