Genetic mutations and abnormal gene regulation are key mechanisms underlying
tumorigenesis. Nucleosomes, which consist of DNA wrapped around histone cores …

A major transcriptional and phenotypic reprogramming event during development is the
establishment of the mesodermal layer from the ectoderm through epithelial-mesenchymal …

A central question in neural tissue engineering is how the tissue-engineered nerve (TEN)
translates detailed transcriptional signals associated with peripheral nerve regeneration into …

Metastasis formation requires active energy production and is regulated at multiple levels by
mitochondrial metabolism. The hyperactive metabolism of cancer cells supports their …

Aging as one of intrinsic biological processes is a risk factor for many chronic diseases.
Kidney disease is a global problem and health care burden worldwide. The diagnosis of …

Whereas cardiomyocytes (CMs) in the fetal heart divide, postnatal CMs fail to undergo
karyokinesis and/or cytokinesis and therefore become polyploid or binucleated, a key …

Zinc finger E‐box binding homeobox 1 (ZEB1), an important transcription factor belonging to
the ZEB family, plays a crucial role in regulating gene expression required for both normal …

Polyunsaturated fatty acids (PUFAs) and their metabolites may influence cell fate regulation.
Herein, we investigated the effects of linoleic acid (LA) as ω‐6 PUFA, eicosapentaenoic acid …

Nitric oxide (NO) is a diffusible signaling molecule produced by three isoforms of nitric oxide
synthase, which release NO during the metabolism of the amino acid arginine. NO …

Aims Understanding the molecular identity of human pluripotent stem cell (hPSC)-derived
cardiac progenitors and mechanisms controlling their proliferation and differentiation is …