Transmitted HIV-1 is more virulent in heterosexual individuals than men-who-have-sex-with-men

A James, NM Dixit - PLoS Pathogens, 2022 - journals.plos.org
Transmission bottlenecks introduce selection pressures on HIV-1 that vary with the mode of
transmission. Recent studies on small cohorts have suggested that stronger selection …

Increasing proportions of HIV-1 non-B subtypes and of NNRTI resistance between 2013 and 2016 in Germany: Results from the national molecular surveillance of …

A Hauser, A Hofmann, K Meixenberger, B Altmann… - PloS one, 2018 - journals.plos.org
Background Molecular surveillance of newly diagnosed HIV-infections is important for
tracking trends in circulating HIV-variants, including those with transmitted drug resistances …

Rare occurrence of doravirine resistance-associated mutations in HIV-1-infected treatment-naive patients

C Soulie, MM Santoro, C Charpentier… - Journal of …, 2019 - academic.oup.com
Background Doravirine is a novel HIV-1 NNRTI recently shown to be non-inferior to both
darunavir/ritonavir and efavirenz in combination therapy with two NRTIs in treatment-naive …

Quantification of HIV-DNA and residual viremia in patients starting ART by droplet digital PCR: Their dynamic decay and correlations with immunological parameters …

C Alteri, R Scutari, C Stingone, G Maffongelli… - Journal of Clinical …, 2019 - Elsevier
Background Accurate quantification of total HIV-DNA and residual-viremia by sensitive
assays is extremely useful to optimize monitoring of ART-treated patients. Objectives To …

Evolution of transmitted HIV‐1 drug resistance and viral subtypes circulation in Italy from 2006 to 2016

B Rossetti, S Di Giambenedetto, C Torti… - HIV …, 2018 - Wiley Online Library
Objectives The aim was to evaluate the evolution of transmitted HIV‐1 drug resistance (TDR)
prevalence in antiretroviral therapy (ART)‐naïve patients from 2006 to 2016. Methods HIV‐1 …

[HTML][HTML] Transmitted drug resistance mutations and trends of HIV-1 subtypes in treatment-naive patients: a single-centre experience

L Mazzuti, T Melengu, F Falasca, M Calabretto… - Journal of Global …, 2020 - Elsevier
Objectives Transmitted drug resistance (TDR) and HIV-1 genetic diversity may affect
treatment efficacy and clinical outcomes. Here we describe the circulating viral subtypes and …

HIV-1 transmitted drug resistance in newly diagnosed individuals in Italy over the period 2015–21

L Fabeni, D Armenia, I Abbate… - Journal of …, 2024 - academic.oup.com
Background Transmitted drug resistance (TDR) is still a critical aspect for the management
of individuals living with HIV-1. Thus, its evaluation is crucial to optimize HIV care. Methods …

Characterisation of HIV-1 molecular transmission clusters among newly diagnosed individuals infected with non-B subtypes in Italy

L Fabeni, C Alteri, G Berno, R Scutari, N Orchi… - Sexually Transmitted …, 2019 - sti.bmj.com
Objective We evaluated the characteristics of HIV-1 molecular transmission clusters (MTCs)
in 1890 newly diagnosed individuals infected with non-B subtypes between 2005 and 2017 …

Evaluation of HIV transmission clusters among natives and foreigners living in Italy

L Fabeni, MM Santoro, P Lorenzini, S Rusconi… - Viruses, 2020 - mdpi.com
We aimed at evaluating the characteristics of HIV-1 molecular transmission clusters (MTCs)
among natives and migrants living in Italy, diagnosed between 1998 and 2018 …

A nationwide study about the dispersal patterns of the predominant HIV-1 subtypes A1 and B in Greece: Inference of the molecular transmission clusters

EG Kostaki, M Gova, G Adamis, G Xylomenos, M Chini… - Viruses, 2020 - mdpi.com
Our aim was to investigate the dispersal patterns and parameters associated with local
molecular transmission clusters (MTCs) of subtypes A1 and B in Greece (predominant HIV-1 …