The intestinal epithelium, composed of at least seven differentiated cell types, represents an
extraordinary model to understand the details of multi-lineage differentiation, a question that …

Small cell lung cancer (SCLC) is widely considered to be a tumor of pulmonary
neuroendocrine cells; however, a variant form of this disease has been described that lacks …

Cilia are microscopic projections that extend from eukaryotic cells. There are two general
types of cilia; primary cilia serve as sensory organelles, whereas motile cilia exert …

Steviol glycosides (SGs), such as stevioside and rebaudioside A, are natural, non-caloric
sweet-tasting organic molecules, present in extracts of the scrub plant Stevia rebaudiana …

The upper respiratory tract is continually assaulted with harmful dusts and xenobiotics
carried on the incoming airstream. Detection of such irritants by the trigeminal nerve evokes …

Tuft cells—rare solitary chemosensory cells in mucosal epithelia—are undergoing intense
scientific scrutiny fueled by recent discovery of unsuspected connections to type 2 immunity …

Approximately 20 of the 30 mammalian transient receptor potential (TRP) channel subunits
are expressed by specific neurons and cells within the alimentary canal. They subserve …

In the epithelium of the lower airways, a cell type of unknown function has been termed
“brush cell” because of a distinctive ultrastructural feature, an apical tuft of microvilli …

Taste buds are the transducing endorgans of gustation. Each taste bud comprises 50–100
elongated cells, which extend from the basal lamina to the surface of the tongue, where their …

Transient receptor potential channel M5 (Trpm5)-expressing cells, such as sweet, umami,
and bitter taste cells in the oropharyngeal epithelium, solitary chemosensory cells in the …