Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy

Z Kejík, J Hajduch, N Abramenko, F Vellieux… - Communications …, 2024 - nature.com
Mitochondrial dysregulation plays a significant role in the carcinogenesis. On the other
hand, its destabilization strongly represses the viability and metastatic potential of cancer …

[HTML][HTML] Solid lipid nanoparticles and their application in the treatment of bacterial infectious diseases

MR Arabestani, A Bigham, F Kamarehei, M Dini… - Biomedicine & …, 2024 - Elsevier
Nano pharmacology is considered an effective, safe, and applicable approach for drug
delivery applications. Solid lipid nanoparticle (SLNs) colloids contain biocompatible lipids …

Photosensitizers for photodynamic therapy: Structure-activity analysis of cyanine dyes through design of experiments

C Pontremoli, G Chinigò, S Galliano, MJM Plata… - Dyes and …, 2023 - Elsevier
In this work, a new series of pentamethine indolenine cyanine dyes has been designed and
synthesized with the aim to investigate a structure-activity relationship on their photodynamic …

NIR squaraine dyes for dual colorimetric and fluorescent determination of Fe 3+, Cu 2+, and Hg 2+ ions

H Li, Y Tang, K Shen, J Lu, Z Zhang, D Yi, N Hao… - RSC …, 2023 - pubs.rsc.org
Four benzoindolenine-based squaraine dyes (SQs), which have the advantages of intense
visible and near-infrared (NIR) absorption and emission (λabs/max 663–695 nm, λem/max …

[HTML][HTML] Squaraine-loaded mesoporous silica nanoparticles for antimicrobial Photodynamic Therapy against bacterial infection

DM Dereje, A García, C Pontremoli, B González… - Microporous and …, 2024 - Elsevier
Antimicrobial photodynamic therapy (aPDT) shows promise as a complementary or
alternative approach to conventional antimicrobial treatments. Despite possessing some key …

Hafnium-Based Metal–Organic Framework Nanosystems Entrapping Squaraines for Efficient NIR-Responsive Photodynamic Therapy

S Rojas-Buzo, C Pontremoli, S De Toni… - … Applied Materials & …, 2025 - ACS Publications
In this study, we present for the first time the incorporation of two distinct nonsymmetrical
squaraines (SQ) into hierarchically porous Hafnium-based UiO-66 Metal–Organic …

A quality by design approach for the synthesis of palmitoyl-L-carnitine-loaded nanoemulsions as drug delivery systems

EM Arroyo-Urea, M Muñoz-Hernando… - Drug Delivery, 2023 - Taylor & Francis
Nanoemulsions (NE) are lipid nanocarriers that can efficiently load hydrophobic active
compounds, like palmitoyl-L-carnitine (pC), used here as model molecule. The use of design …

Quantitative photoacoustic spectral transformations in theranostic solid lipid nanoparticles labelled with increasing concentrations of a photoacoustic NIR BODIPY

C Linger, G Maccini, G Clavier, R Méallet, N Tsapis… - Nanoscale, 2025 - pubs.rsc.org
Solid lipid nanoparticles (SLNs) have shown great capabilities for drug delivery and are
therefore attractive theranostic candidates when labelled with an imaging contrast agent …

Quatsomes loaded with squaraine dye as an effective photosensitizer for photodynamic therapy

N Bordignon, M Köber, G Chinigò, C Pontremoli… - Pharmaceutics, 2023 - mdpi.com
Photodynamic therapy is a non-invasive therapeutic strategy that combines external light
with a photosensitizer (PS) to destroy abnormal cells. Despite the great progress in the …

The potential of TRP channels as new prognostic and therapeutic targets against prostate cancer progression

G Chinigò, FA Ruffinatti, L Munaron - … et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Prostate cancer (PCa) is the second deadliest cancer among men worldwide. Particularly
critical is its development towards metastatic androgen-independent forms for which the …