Synthesis and reactivity of propargylamines in organic chemistry

K Lauder, A Toscani, N Scalacci… - Chemical reviews, 2017 - ACS Publications
Propargylamines are a versatile class of compounds which find broad application in many
fields of chemistry. This review aims to describe the different strategies developed so far for …

A3 Coupling Reaction in the Synthesis of Heterocyclic Compounds

Y Volkova, S Baranin, I Zavarzin - Advanced Synthesis & …, 2021 - Wiley Online Library
In recent years, the transition‐metal catalyzed three‐component coupling of an aldehyde, an
alkyne and an amine, commonly called A3 coupling has become a powerful tool in organic …

Dendrimer templated ionic liquid nanomagnetic for efficient coupling reactions

S Peiman, B Maleki, M Ghani - Scientific Reports, 2024 - nature.com
In this research, a logical strategy with a recyclable synthetic perspective of view and a
rational design to prepare a nanocatalyst with a dendrimer template containing ionic liquid is …

Recent Advances in the A3 Coupling Reactions and their Applications

I Jesin, GC Nandi - European Journal of Organic Chemistry, 2019 - Wiley Online Library
Propargylamines are an important class of organic compounds that have been widely used
as building blocks for the synthesis of various kinds of chemically and biologically relevant …

Investigation of DNA binding and bioactivities of thioether containing Schiff base Copper (II), Cobalt (II) and Palladium (II) complexes: Synthesis, characterization …

SK Maiti, M Kalita, A Singh, J Deka, P Barman - Polyhedron, 2020 - Elsevier
Three complexes of an ONS donor ligand of the Schiff base [C 21 H 19 NO 2 S](HL),[Cu (C
21 H 18 NO 2 S) 2](1)[Co (C 21 H 18 NO 2 S) 2](2) and [Pd (C 21 H 18 NO 2 SCl)](3), were …

Metal-Catalysed A3 Coupling Methodologies: Classification and Visualisation

J Farhi, IN Lykakis, GE Kostakis - Catalysts, 2022 - mdpi.com
The multicomponent reaction of aldehydes, amines, and alkynes, known as A3 coupling,
yields propargylamines, a valuable organic scaffold, and has received significant interest …

Enantioselective A3 Reactions of Secondary Amines with a Cu(I)/Acid–Thiourea Catalyst Combination

C Zhao, D Seidel - Journal of the American Chemical Society, 2015 - ACS Publications
Pyrrolidine and related amines undergo asymmetric A3 reactions in the presence of copper
iodide and an easily accessible cocatalyst possessing both a carboxylic acid and a thiourea …

Pyrinap ligands for enantioselective syntheses of amines

Q Liu, H Xu, Y Li, Y Yao, X Zhang, Y Guo… - Nature …, 2021 - nature.com
Amines are a class of compounds of essential importance in organic synthesis,
pharmaceuticals and agrochemicals. Due to the importance of chirality in many practical …

The Asymmetric A3(Aldehyde–Alkyne–Amine) Coupling: Highly Enantioselective Access to Propargylamines

JN Mo, J Su, J Zhao - Molecules, 2019 - mdpi.com
The recent developments in asymmetric A3 (aldehyde–alkyne–amine) coupling has been
summarized in this review. Several interesting modifications of the ligands enabled the …

Zn (II) anchored onto the magnetic natural hydroxyapatite (Zn II/HAP/Fe 3 O 4): as a novel, green and recyclable catalyst for A 3-coupling reaction towards …

Z Zarei, B Akhlaghinia - RSC Advances, 2016 - pubs.rsc.org
In this paper, Zn (II) anchored onto the magnetic natural hydroxyapatite (ZnII/HAP/Fe3O4),
as a new, versatile and magnetically recoverable catalyst, was prepared and characterized …