Synthetic gene regulation in cyanobacteria

CM Immethun, TS Moon - Synthetic biology of cyanobacteria, 2018 - Springer
Cyanobacteria are appealing hosts for green chemical synthesis due to their use of light and
carbon dioxide. To optimize product yields and titers, specific and tunable regulation of the …

[图书][B] Synthetic biology of cyanobacteria

W Zhang, X Song - 2018 - Springer
The world is facing several major challenges, particularly issues related to resource crisis
and environmental pollution. To address these challenges, in recent decades …

Executable biochemical space for specification and analysis of biochemical systems

M Troják, D Šafránek, L Brim, J Šalagovič… - Electronic Notes in …, 2020 - Elsevier
We present the second generation of a rule-based language called Biochemical Space
Language (BCSL) that combines the advantages of different approaches and thus makes an …

Regulated multiset rewriting systems

M Troják, S Pastva, D Šafránek, L Brim - arXiv preprint arXiv:2111.13036, 2021 - arxiv.org
Multiset rewriting systems provide a formalism particularly suitable for the description of
biological systems. We present an extension of this formalism with additional controls on the …

Fully automated attractor analysis of cyanobacteria models

N Beneš, L Brim, S Pastva, D Šafránek… - … on System Theory …, 2018 - ieeexplore.ieee.org
Complex dynamics arising in biological systems can be characterised by various kinds of
attractors. To that end, the task of determining attractors becomes important in modern …

Parameter synthesis and robustness analysis of rule-based models

M Troják, D Šafránek, L Mertová, L Brim - … , Moffett Field, CA, USA, May 11 …, 2020 - Springer
Abstract We introduce the Quantitative Biochemical Space Language, a rule-based
language for a compact modelling of probabilistic behaviour of complex parameter …

Facetal abstraction for non-linear dynamical systems based on δ-decidable SMT

N Beneš, L Brim, J Dražanová, S Pastva… - Proceedings of the 22nd …, 2019 - dl.acm.org
Formal analysis of non-linear continuous and hybrid systems is a hot topic. A common
approach builds on computing a suitable finite discrete abstraction of the continuous system …

[PDF][PDF] Framework for automatised annotation of biochemical entities

L Mertová - Masaryk University, 2020 - is.muni.cz
This work deals with computer-aided annotation of entities in biochemical databases.
Annotation in systems biology means combining biochemical entities from computational …

[PDF][PDF] Webová komponenta pro vizualizaci parametrického prostoru

M PETR - is.muni.cz
Rád bych poděkoval vedoucímu práce doc. RNDr. Davidovi Šafrán kovi, Ph. D., za pomoc
při psaní práce, velmi ochotný přístup a věcné rady. Dále bych chtěl poděkovat RNDr. Matěji …

[PDF][PDF] Comprehensive modelling platform for epidemic dynamics

R Doktor - is.muni.cz
Modelling of epidemics is a well-studied area that requires the development of novel models
due to the high variability of the diseases. A fitting example is the outbreak of SARS-COV-2 …