The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

Nitrogen heterocyclic rings have participated to constitute most of the drugs and several
pharmacologically related compounds. The existence of such hetero atoms/groups in …

In this study, a new series of quinazoline derivatives (3–26) was synthesized and
characterized via physicochemical and spectral means. Treatment of 2-amino-5 …

Optimisation at B3LYP/6-311G (d, p) was used in a DFT study of the characteristics of 2-
methylthio (methylsulfonyl)-triazoloquinazolines (1, 2). The design-critical role of …

Previously, we synthesized triazoloquinazolines 1–14 and characterized their structure. In
this study, we aimed to evaluate the in vitro activity of the targets 1–14 as α-glucosidase …

A series of 1, 2, 4-triazolo-quinazolinones and 1, 2-benzisothiazolone derivatives (S1–S12)
were successfully synthesized as environmentally friendly alternatives to copper-based …

Fourteen triazole benzoic acid hybrids were previously characterized. This work aimed to
screen their in vitro antioxidant activity using different assays, ie, DPPH (1, 1-diphenyl-1 …

Aim: The present study was carried out to assess a new series of triazoloquinazolines 1–40
for their antioxidant activities using 1, 1-diphenyl-2-picryl hydrazyl radical scavenging, ferric …

Novel thiazolidine-2, 4-dione (TZD) based pyrimidine derivatives have been synthesized by
Knoevenagel condensation reaction between thiazolidine-2, 4-dione and amino pyrimidinyl …

Diabetes is an emerging metabolic disorder. α-Glucosidase inhibitors, such as acarbose,
delay the hydrolysis of carbohydrates by interfering with the digestive enzymes. This action …