In this study, we report novel casein-derived peptide sequences with angiotensin converting
enzyme (ACE)-inhibitory activity and antihypertensive activity demonstrated in …

Background and aims Chronic ethanol consumption is associated with hypertension and
atherosclerosis. Vascular oxidative stress is described as an important mechanism whereby …

Background Although effective in reducing blood pressure, therapy with a first-generation β-
blocker is currently controversial in metabolic syndrome due to its negative impact on …

Objectives: Increased sympathetic outflow, renin–angiotensin system (RAS) activity, and
oxidative stress are critical mechanisms underlying the adverse cardiovascular effects of …

Objectives D/L-Nebivolol is a lypophilic β 1-adrenergic antagonist which is devoid of intrinsic
sympathomimetic activity and can increase nitric oxide (NO) bioavailability with its …

Strong evidence supports the idea that total peripheral resistance (TPR) is increased in all
forms of human and experimental hypertension. Although the etiological participation of TPR …

Objectives We observed previously that nebivolol treatment for 2 months reduced
cardiovascular lesions in spontaneously hypertensive rats (SHR). Therefore, we …

Abstract β-Adrenergic blockers are no longer recommended as first-line therapy due to the
reduced cardioprotection of traditional β-blockers compared with other antihypertensive …

Objective: The objective of this article is to assess the effects of nebivolol on resistant
vascular reactivity, ventricular hypertrophy and the renin–angiotensin system in …

BACKGROUND: Rhabdomyolysis (RM)-induced acute renal failure (ARF) accounts for
about 10–40% of all cases of ARF. AIM: The present study investigated the possible …