Mycobacterium tuberculosis is an old enemy of the human race, with evidence of infection
observed as early as 5000 years ago. Although more host-restricted than Mycobacterium …

Lungs are directly exposed to the air, have enormous surface area, and enable gas
exchange in air-breathing animals. They are constantly 'attacked'by microbes from both …

Immunity to Mycobacterium tuberculosis in humans and in mice requires interferon gamma
(IFN-γ). Whereas IFN-γ has been studied extensively for its effects on macrophages in …

Inhalation exposure to indoor air pollutants and cigarette smoke increases the risk of
developing tuberculosis (TB). Whether exposure to ambient air pollution particulate matter …

Tuberculosis (TB), an infectious disease caused by the pathogen Mycobacterium
tuberculosis (Mtb), kills about 1.5 million people every year worldwide. An increase in the …

Tuberculosis is an ongoing threat to global health, especially with the emergence of multi
drug-resistant (MDR) and extremely drug-resistant strains that are motivating the search for …

Tuberculosis (TB) is a major worldwide health problem in part due to the lack of
development of new treatments and the emergence of new strains such as multidrug …

Tuberculosis (TB) is the outcome of an insidious, protracted infection with Mycobacterium
tuberculosis (Mtb). It primarily affects the lung and is characterized by extensive focal …

Tuberculosis, which is caused by infection with Mycobacterium tuberculosis (Mtb), remains
one of the major bacterial infections worldwide. Host defense against Mtb is mediated by a …

Tuberculosis (TB) is characterized by extensive pulmonary matrix breakdown. Interleukin‐17
(IL‐17) is key in host defence in TB but its role in TB‐driven tissue damage is unknown. We …