Living donor liver transplantation (LDLT) is recognised as an alternative treatment modality
to reduce waiting list mortality and expand the donor pool. Over recent decades, there have …

ABSTRACT Background Liver transplantation (LTx) constitutes a major life‐saving routine
treatment for children with end‐stage liver disease. However, the analysis of LTx registries in …

Several diseases originate from bile duct pathology. Despite studies on these diseases,
certain etiologies of some of them still cannot be concluded. The most common disease of …

Introduction Alagille syndrome (ALGS) is an autosomal dominant, multisystem genetic
disorder with wide phenotypic variability caused by mutations in the Notch signaling …

Pediatric genetic and metabolic liver diseases comprise a broad spectrum of conditions and
represent the second most common indication for liver transplantation following biliary …

Aim: Alagille syndrome (ALGS) is a rare, cholestatic multiorgan disease associated with bile
duct paucity, leading to cholestasis. Clinical symptoms of cholestasis include debilitating …

Alagille syndrome (AGS) is one of the most problematic for the diagnosis of hereditary,
multisystem, cholestatic liver diseases in combination with other congenital defects. Timely …

Background Infants with Alagille syndrome (ALGS) need to be promptly differentiated from
biliary atresia (BA) at an early stage. ALGS is an autosomal, dominant, multisystem disorder …

Children with cholestatic liver diseases are increasingly living into adulthood, thanks to
innovations in medical and surgical therapies. The excellent outcomes observed in pediatric …

Arteriopathies are important causes of stroke. These can be acquired or inherited. Most
genetic causes of vasculopathy can be classified by the types of vessels that they affect …