Magnesium as an enzymatic activator is essential for various physiological functions such as
cell cycle, metabolic regulation, muscle contraction, and vasomotor tone. A growing body of …

Cisplatin is one of the most widely used chemotherapeutic drugs in the treatment of a wide
range of pediatric and adult malignances. However, it has various side effects which limit its …

Cisplatin, as a commonly used anticancer drug, can easily lead to acute kidney injury (AKI),
and has received more and more attention in clinical practice. β-hydroxybutyric acid (BHB) is …

Background: Worldwide, lung cancer is one of the leading causes of cancer death.
Nevertheless, new therapeutic agents have been developed to treat lung cancer that could …

Reactive oxygen species (ROS) scavenging therapy toward acute kidney injury (AKI) is
promising, but no effective ROS scavenging drug has been developed yet. Moreover, cell …

Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a
variety of solid-cancers, substantially improving the five-year survival rates for cancer …

Cisplatin is extensively used to treat malignancies. However, its clinical use is always limited
due to the serious side effects, especially the nephrotoxicity. Matrine (MAT), a tetracyclic …

Extracellular vesicle (EV)‐based therapies have emerged as a promising means in
regenerative medicine. However, the conventional EV therapy strategy displays some …

Conventional chemotherapies remain the mainstay of treatment for many malignancies.
Kidney complications of these therapies are not infrequent and may have serious …

Cisplatin (CP) is a broad-spectrum antineoplastic agent, used to treat many different types of
malignancies due to its high efficacy and low cost. However, its use is largely limited by …