Translation in prokaryotes
MV Rodnina - Cold Spring Harbor perspectives in …, 2018 - cshperspectives.cshlp.org
This review summarizes our current understanding of translation in prokaryotes, focusing on
the mechanistic and structural aspects of each phase of translation: initiation, elongation …
the mechanistic and structural aspects of each phase of translation: initiation, elongation …
tRNA modifications: impact on structure and thermal adaptation
C Lorenz, CE Lünse, M Mörl - Biomolecules, 2017 - mdpi.com
Transfer RNAs (tRNAs) are central players in translation, functioning as adapter molecules
between the informational level of nucleic acids and the functional level of proteins. They …
between the informational level of nucleic acids and the functional level of proteins. They …
Thoughts on how to think (and talk) about RNA structure
Recent events have pushed RNA research into the spotlight. Continued discoveries of RNA
with unexpected diverse functions in healthy and diseased cells, such as the role of RNA as …
with unexpected diverse functions in healthy and diseased cells, such as the role of RNA as …
Structure of the bacterial ribosome at 2 Å resolution
ZL Watson, FR Ward, R Méheust, O Ad, A Schepartz… - elife, 2020 - elifesciences.org
Using cryo-electron microscopy (cryo-EM), we determined the structure of the Escherichia
coli 70S ribosome with a global resolution of 2.0 Å. The maps reveal unambiguous …
coli 70S ribosome with a global resolution of 2.0 Å. The maps reveal unambiguous …
Structure of the human 80S ribosome
H Khatter, AG Myasnikov, SK Natchiar, BP Klaholz - Nature, 2015 - nature.com
Ribosomes are translational machineries that catalyse protein synthesis. Ribosome
structures from various species are known at the atomic level, but obtaining the structure of …
structures from various species are known at the atomic level, but obtaining the structure of …
The complete structure of the 55S mammalian mitochondrial ribosome
Mammalian mitochondrial ribosomes (mitoribosomes) synthesize mitochondrially encoded
membrane proteins that are critical for mitochondrial function. Here we present the complete …
membrane proteins that are critical for mitochondrial function. Here we present the complete …
Structural basis of early translocation events on the ribosome
Peptide-chain elongation during protein synthesis entails sequential aminoacyl-tRNA
selection and translocation reactions that proceed rapidly (2–20 per second) and with a low …
selection and translocation reactions that proceed rapidly (2–20 per second) and with a low …
Structures of the human and Drosophila 80S ribosome
Protein synthesis in all cells is carried out by macromolecular machines called ribosomes.
Although the structures of prokaryotic, yeast and protist ribosomes have been determined …
Although the structures of prokaryotic, yeast and protist ribosomes have been determined …
Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM
Single particle electron cryomicroscopy (cryo-EM) has recently made significant progress in
high-resolution structure determination of macromolecular complexes due to improvements …
high-resolution structure determination of macromolecular complexes due to improvements …
The structure of the human mitochondrial ribosome
The highly divergent ribosomes of human mitochondria (mitoribosomes) synthesize 13
essential proteins of oxidative phosphorylation complexes. We have determined the …
essential proteins of oxidative phosphorylation complexes. We have determined the …