[HTML][HTML] Acquired HIV drug resistance mutations on first-line antiretroviral therapy in Southern Africa: Systematic review and Bayesian evidence synthesis
A Hauser, F Goldstein, ML Reichmuth… - Journal of clinical …, 2022 - Elsevier
Objective: To estimate the prevalence of NRTI and NNRTI drug resistance mutations in
patients failing NNRTI-based ART in Southern Africa. Study design: We conducted a …
patients failing NNRTI-based ART in Southern Africa. Study design: We conducted a …
PANGEA-HIV 2: phylogenetics and networks for generalised epidemics in Africa
L Abeler-Dörner, MK Grabowski… - Current Opinion in …, 2019 - journals.lww.com
Combining phylogenetics, phylodynamics and epidemiology will allow PANGEA to highlight
where prevention efforts should be focussed to reduce the HIV epidemic most effectively. To …
where prevention efforts should be focussed to reduce the HIV epidemic most effectively. To …
Differential effects of antiretroviral treatment on immunity and gut microbiome composition in people living with HIV in rural versus urban Zimbabwe
AS Burkhart Colorado, A Lazzaro, CP Neff… - Microbiome, 2024 - Springer
Background The widespread availability of antiretroviral therapy (ART) has dramatically
reduced mortality and improved life expectancy for people living with HIV (PLWH). However …
reduced mortality and improved life expectancy for people living with HIV (PLWH). However …
Occult HIV-1 drug resistance to thymidine analogues following failure of first-line tenofovir combined with a cytosine analogue and nevirapine or efavirenz in sub …
J Gregson, P Kaleebu, VC Marconi… - The Lancet infectious …, 2017 - thelancet.com
Background HIV-1 drug resistance to older thymidine analogue nucleoside reverse
transcriptase inhibitor drugs has been identified in sub-Saharan Africa in patients with …
transcriptase inhibitor drugs has been identified in sub-Saharan Africa in patients with …
Simplifying switch to second-line antiretroviral therapy in sub Saharan Africa: predicted effect of using a single viral load to define efavirenz-based first-line failure
A Shroufi, G Van Cutsem, V Cambiano… - Aids, 2019 - journals.lww.com
Background: Many individuals failing first-line antiretroviral therapy (ART) in sub-Saharan
Africa never initiate second-line ART or do so after significant delay. For people on ART with …
Africa never initiate second-line ART or do so after significant delay. For people on ART with …
Adoption of routine virologic testing and predictors of virologic failure among HIV-infected children on antiretroviral treatment in western Kenya
J Kadima, E Patterson, M Mburu, C Blat, M Nyanduko… - PloS one, 2018 - journals.plos.org
Background Access to routine virologic monitoring, critical to ensuring treatment success,
remains limited in low-and middle-income countries. We report on implementation of routine …
remains limited in low-and middle-income countries. We report on implementation of routine …
High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa
EM Etta, L Mavhandu, C Manhaeve… - AIDS research and …, 2017 - Springer
Background Combination antiretroviral therapy (cART) has significantly reduced HIV
morbidity and mortality in both developed and developing countries. However, the …
morbidity and mortality in both developed and developing countries. However, the …
Incidence and predictors of treatment failure among children receiving first-line antiretroviral treatment in general hospitals of two zones, Tigray, Ethiopia, 2019
Background Despite many efforts undertaken to control the human immunodeficiency virus
epidemic, it remains to be the major global public health challenge. With expanding access …
epidemic, it remains to be the major global public health challenge. With expanding access …
[HTML][HTML] Antiretroviral treatment failure among HIV-positive adults taking first-line therapy and associated risk factors at Adigrat General hospital, Adigart, Ethiopia 2019 …
DG Demsie, AT Bantie, MD Allene, NM Alema… - International Journal of …, 2020 - Elsevier
Abstract Background Human Immunodeficiency Virus (HIV) is a major public health problem
globally. Highly active antiretroviral therapy (HAART) has led to profound reduction in the …
globally. Highly active antiretroviral therapy (HAART) has led to profound reduction in the …
Drug resistance mutations against protease, reverse transcriptase and integrase inhibitors in people living with HIV-1 receiving boosted protease inhibitors in South …
The South African national combination antiretroviral therapy (cART) roll-out program started
in 2006, with over 4.4 million people accessing treatment since it was first introduced. HIV-1 …
in 2006, with over 4.4 million people accessing treatment since it was first introduced. HIV-1 …