Tendon injuries are at the frontier of innovative approaches to public health concerns and
sectoral policy objectives. Indeed, these injuries remain difficult to manage due to tendon's …

Chronic tendinopathy is a debilitating tendon disorder with disappointing treatment
outcomes. This review focuses on the potential roles of chronic low-grade inflammation in …

Cells integrate mechanical cues to direct fate specification to maintain tissue function and
homeostasis. While disruption of these cues is known to lead to aberrant cell behavior and …

Recent experimental evidence indicates potential adverse effects of statin treatment on
tendons but previous clinical studies are few and inconclusive. The aims of our study were …

Tendon rupture induces an inflammatory response characterized by release of pro-
inflammatory cytokines and impaired tendon performance. This study sought to investigate …

This review delves into the intersection of two prevalent conditions, hyperlipidemia and
rotator cuff injuries, both of which bear substantial healthcare burdens. Our investigation …

Matrix metalloproteinases (MMPs) are a family of endopeptidases, mainly responsible of
extracellular tissue remodeling. Abundant expression of MMPs leads to a number of …

Tendinopathy is a disease with surging prevalence. Lacking understanding of molecular
mechanisms impedes the development of therapeutic approaches and agents. Lysine …

Introduction Statins are widely used to inhibit cholesterol production in the liver among
people with hypercholesterolemia. A recent epidemiological study in the UK has shown that …

Critical-size bone defects are one of the main challenges in bone tissue regeneration that
determines the need to use angiogenic and osteogenic agents. Rosuvastatin (RSV) is a …