Ion channels are key regulators of cancer cell pathophysiology. They contribute to a variety
of processes such as maintenance of cellular osmolarity and membrane potential, motility …

Membrane-associated estrogen receptors (ER)-α36 and G protein-coupled estrogen
receptor (GPER) play important roles in the estrogen's rapid non-genomic actions including …

Bergamot, a Mediterranean citrus fruit native to southern Italy, has been reported to have
cholesterol-lowering properties; however, the mechanism of action is not well understood …

Breast cancer is a common malignancy in women. Among breast cancer types, triple-
negative breast cancer (TNBC) tends to affect younger women, is prone to axillary lymph …

Simple Summary TRPV6 is a highly selective channel for calcium ions and plays an
important role in maintaining calcium homeostasis. Some evidence suggests that it is …

Introduction: Metabolic disorders are an important health concern that threatens life and
burdens society severely. ClC-3 is a member of the chloride voltage-gated channel family …

Chloride channel 3 (ClC-3), a Cl−/H+ antiporter, has been well established as a member of
volume-regulated chloride channels (VRCCs). ClC-3 may be a crucial mediator for …

ATP 结合盒(ABC) 转运蛋白表达和功能的异常是造成多药耐药(MDR) 的重要原因之一, 其中P-
糖蛋白, 乳腺癌耐药蛋白和MDR 相关蛋白在MDR 发生中起着重要作用, 是ABC …

Objectives Adult stem cells uphold a delicate balance between quiescent and active states,
which is crucial for tissue homeostasis. Whereas many signalling pathways that regulate …

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