Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O) or
oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as …

Applications of nanotechnology in various spheres have increased manifold as it offers
solution to unsolved problems with higher effectiveness. Nanoemulsions are one such …

The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

The blood–brain barrier (BBB) plays a fundamental role in protecting the brain from toxic
substances and therefore also controls and restricts the entry of therapeutic agents. The …

Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

The treatment of various central nervous system (CNS) diseases has been challenging,
despite the rapid development of several novel treatment approaches. The blood–brain …

We designed a delivery system to obtain an efficient and optimal nose-to-brain transport of
BACE1 siRNA, potentially useful in the treatment of Alzheimer's disease. We selected a cell …

The research work was intended to formulate teriflunomide (TFM) loaded nano lipid-based
(TNLC) carbopol-gellan gum in situ gel (TNLCGHG) and to investigate its therapeutic …

Ischemic stroke is caused by a reduction in blood flow to the brain due to narrowed cerebral
arteries. Thrombolytic agents have been used to induce reperfusion of occluded cerebral …

Nucleic acid drugs have the advantages of rich target selection, simple in design, good and
enduring effect. They have been demonstrated to have irreplaceable superiority in brain …