[HTML][HTML] A critical review of Astragalus polysaccharides: from therapeutic mechanisms to pharmaceutics

Y Du, H Wan, P Huang, J Yang, Y He - Biomedicine & pharmacotherapy, 2022 - Elsevier
As the important active ingredients of Astragali Radix (AR), Astragalus polysaccharides
(APs) have therapeutic potential for multiple diseases including nervous system diseases …

Modulatory effects of polysaccharides from plants, marine algae and edible mushrooms on gut microbiota and related health benefits: A review

H Zhang, F Jiang, J Zhang, W Wang, L Li… - International Journal of …, 2022 - Elsevier
Naturally occurring carbohydrate polymers containing non-starch polysaccharides (NPs) are
a class of biomacromolecules isolated from plants, marine algae, and edible mushrooms …

Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

JP Shaffer, LF Nothias, LR Thompson, JG Sanders… - Nature …, 2022 - nature.com
Despite advances in sequencing, lack of standardization makes comparisons across studies
challenging and hampers insights into the structure and function of microbial communities …

Desulfovibrio vulgaris, a potent acetic acid-producing bacterium, attenuates nonalcoholic fatty liver disease in mice

Y Hong, L Sheng, J Zhong, X Tao, W Zhu, J Ma… - Gut …, 2021 - Taylor & Francis
The emerging evidence supports the use of prebiotics like herb-derived polysaccharides for
treating nonalcoholic fatty liver disease (NAFLD) by modulating gut microbiome. The present …

Astragalus mongholicus polysaccharides ameliorate hepatic lipid accumulation and inflammation as well as modulate gut microbiota in NAFLD rats

M Zhong, Y Yan, H Yuan, A Rong, G Xu, F Cai… - Food & Function, 2022 - pubs.rsc.org
Hepatic lipid accumulation, inflammation and gut microbiota dysbiosis are hallmarks of non-
alcoholic fatty liver disease (NAFLD), which is the leading cause of chronic liver disease with …

Akkermansia muciniphila: is it the Holy Grail for ameliorating metabolic diseases?

J Yan, L Sheng, H Li - Gut Microbes, 2021 - Taylor & Francis
The increasing prevalence of metabolic diseases has become a severe public health
problem. Gut microbiota play important roles in maintaining human health by modulating the …

Polysaccharides from Alpinia oxyphylla fruit prevent hyperuricemia by inhibiting uric acid synthesis, modulating intestinal flora and reducing renal inflammation

F Ren, J Lin, M Zhu, R Ma, M Zhang, W Chen… - International Journal of …, 2024 - Elsevier
Hyperuricemia (HUA) is one of the most common chronic diseases today, with a prevalence
exceeding 14% in both the United States and China. Current clinical treatments for HUA …

Astragalus polysaccharides and saponins alleviate liver injury and regulate gut microbiota in alcohol liver disease mice

J Zhou, N Zhang, L Zhao, W Wu, L Zhang, F Zhou, J Li - Foods, 2021 - mdpi.com
Astragalus, a medical and edible plant in China, shows several bioactive properties.
However, the role of astragalus in attenuating alcoholic liver disease (ALD) is less clear. The …

Astragalus polysaccharides mediate the immune response and intestinal microbiota in grass carp (Ctenopharyngodon idellus)

F Shi, Z Lu, M Yang, F Li, F Zhan, L Zhao, Y Li, Q Li, J Li… - Aquaculture, 2021 - Elsevier
The immunomodulatory effect of Astragalus polysaccharides (APS) has been revealed in
aquatic animals. However, the fundamental mechanisms in grass carp (Ctenopharyngodon …

Traditional Chinese medicine in the treatment of nonalcoholic steatohepatitis

M Chen, Y Xie, S Gong, Y Wang, H Yu, T Zhou… - Pharmacological …, 2021 - Elsevier
Nonalcoholic steatohepatitis (NASH) is a common chronic liver disease in clinical practice. It
has been considered that NASH is one of the main causes of chronic liver disease, cirrhosis …