Targeting miRNAs and other non-coding RNAs as a therapeutic approach: an update

E Bayraktar, R Bayraktar, H Oztatlici… - Non-coding RNA, 2023 - mdpi.com
Since the discovery of the first microRNAs (miRNAs, miRs), the understanding of miRNA
biology has expanded substantially. miRNAs are involved and described as master …

From resistance to resilience: Uncovering chemotherapeutic resistance mechanisms; insights from established models

NM Abdelmaksoud, AI Abulsoud, AS Doghish… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Despite the tremendous advances in cancer treatment, resistance to chemotherapeutic
agents impedes higher success rates and accounts for major relapses in cancer therapy …

Current landscape of therapeutic resistance in lung cancer and promising strategies to overcome resistance

A Ashrafi, Z Akter, P Modareszadeh, P Modareszadeh… - Cancers, 2022 - mdpi.com
Simple Summary Despite an initial response to therapy, many lung cancer patients
inevitably develop resistance to therapy leading to decreased duration of response and …

Cancer chemoresistance and its mechanisms: Associated molecular factors and its regulatory role

S Kannampuzha, AV Gopalakrishnan - Medical Oncology, 2023 - Springer
Cancer therapy has advanced from tradition chemotherapy methods to targeted therapy,
novel drug delivery mechanisms, combination therapies etc. Although several novel …

Nanoliposomes for doxorubicin delivery: Reversing drug resistance, stimuli-responsive carriers and clinical translation

M Hashemi, F Ghadyani, S Hasani, Y Olyaee… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is still a major threat to human life that is characterized by abnormal proliferation and
metastasis of cancer cells. Chemotherapy is procedure of using anti-cancer drugs for …

Advances in regulation and function of stearoyl-CoA desaturase 1 in cancer, from bench to bed

Z Guo, X Huo, X Li, C Jiang, L Xue - Science China Life Sciences, 2023 - Springer
Abstract Stearoyl-CoA desaturase 1 (SCD1) converts saturated fatty acids to
monounsaturated fatty acids. The expression of SCD1 is increased in many cancers, and the …

Carbon dots-based nanozyme for drug-resistant lung cancer therapy by encapsulated doxorubicin/siRNA cocktail

H Yu, K Tang, Z Cai, X Lin, Y Huang, T Yu… - International journal …, 2023 - Taylor & Francis
Background Nanomaterials exhibited intrinsic enzyme-like properties due to the unique
properties compared with natural enzyme. Carbon dots (CDs) are an important kind of …

Biosensors for cancer detection: A review

S Sarkar, S Hazra, S Patra, M Gogoi - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
The different types of biosensors and their critical applications across multiple domains for
cancer detection have been analyzed in this review. The biosensors have been categorized …

The emerging roles of sphingosine 1-phosphate and SphK1 in cancer resistance: a promising therapeutic target

SS Alkafaas, MI Elsalahaty, DF Ismail… - Cancer Cell …, 2024 - Springer
Cancer chemoresistance is a problematic dilemma that significantly restrains numerous
cancer management protocols. It can promote cancer recurrence, spreading of cancer, and …

Ferroptosis as ultimate target of cancer therapy

Y Motooka, S Toyokuni - Antioxidants & Redox Signaling, 2023 - liebertpub.com
Significance: The significance of ferroptosis in cancer therapeutics has now been unveiled.
Specific ferroptosis inducers are expected as a promising strategy for cancer treatment …