Glial fibrillary acidic protein (GFAP), a type III intermediate filament, is a marker of mature
astrocytes. The expression of GFAP gene is regulated by many transcription factors (TFs) …

Epilepsy is a group of chronic neurological disorders characterized by recurrent,
spontaneous, and unpredictable seizures. It is one of the most common neurological …

Status epilepticus (SE) is a life-threatening prolonged epileptic seizure. A rapid diagnosis is
fundamental to initiate antiepileptic treatment and to prevent the development of …

Status epilepticus (SE) causes persistent abnormalities in the functioning of neuronal
networks, often resulting in worsening epileptic seizures. Many details of cellular and …

Status epilepticus is a medical emergency with elevated morbidity and mortality rates, and
represents a leading cause of epilepsy-related deaths. Though status epilepticus can occur …

Status epilepticus is a condition resulting either from the failure of the mechanisms
responsible for seizure termination or from the initiation of mechanisms that lead to …

Background Temporal lobe epilepsy (TLE) is the most common form of partial epilepsy and
is accompanied, in one third of cases, by resistance to antiepileptic drugs (AED). Most AED …

Objective Seizures have been shown to increase blood-brain barrier (BBB) permeability, yet
the role of this phenomenon is not fully understood. Additionally, dysfunction of the BBB …

S100B is a 21-kDa protein that is produced and secreted by astrocytes and widely used as a
marker of brain injury in clinical and experimental studies. The majority of these studies are …

Abstract New-Onset Refractory Status Epilepticus (NORSE), including its subtype with a
preceding febrile illness known as FIRES (Febrile Infection-Related Epilepsy Syndrome), is …