The pachychoroid disease spectrum encompasses seven major retinal conditions including
central serous chorioretinopathy (CSC), polypoidal choroidal vasculopathy (PCV), and …

Retinal drusen formation is not only a clinical hallmark for the development of age-related
macular degeneration (AMD) but also for other disorders, such as Alzheimer's disease and …

Understanding the mechanisms that underlie age-related macular degeneration (AMD) has
led to the identification of key molecules. Hypoxia-inducible transcription factors (HIFs) have …

Mouse models are powerful tools for the study of ocular diseases. Alterations in the
morphology and function of the retinal pigment epithelium (RPE) are common features …

The retina is one of the most energy-demanding tissues in the human body. Photoreceptors
in the outer retina rely on nutrient support from the neighboring retinal pigment epithelium …

Metabolite transport is a major function of the retinal pigment epithelium (RPE) to support the
neural retina. RPE dysfunction plays a significant role in retinal degenerative diseases. We …

Purpose To evaluate the association between the choroidal thickness (CT) and the
characteristics of drusen and exudative age-related macular degeneration (AMD) sub …

Age-related macular degeneration (AMD) is a mounting cause of loss of sight in the elderly
in the developed countries, a trend enhanced by the continual ageing of the population …

Purpose (1) To collect a dataset of normative Early Treatment Diabetic Retinopathy Study
(ETDRS) thickness map values for single retinal layers automatically segmented by …

The design of efficient therapies for age-related macular degeneration (AMD) is limited by
our understanding of the pathogenesis of basal deposits, which form between retinal …