The increasing number of people with advanced Alzheimer's disease (AD) represents a
significant psychological and financial cost to the world population. Accurate detection of the …

Polymeric micelles, nanosized assemblies of amphiphilic polymers with a core–shell
architecture, have been used as carriers for various therapeutic compounds. They have …

Preservation of brain health is a worldwide priority. The traditional view is that the major
threats to the ageing brain lie within the brain itself. Consequently, therapeutic approaches …

In this study, the metabolic responses of hypoxic breathing for 1 h to inspired fractions of
10% and 15% oxygen were investigated. To this end, 14 healthy nonsmoking subjects (6 …

Background The neurofilament light chain (NfL) assay is gradually becoming an essential
diagnostic tool for the diagnosis of many neurological diseases including amyotrophic …

High‐altitude (HA) hypoxia may alter the structural–functional integrity of the neurovascular
unit (NVU). Herein, we compared male lowlanders (n= 9) at sea level (SL) and after 14 days …

Although the cause (s) of Alzheimer's disease in the majority of cases remains elusive, it has
long been associated with hypertension. In animal models of the disease, hypertension has …

Intermittent hypoxia (IH) is commonly associated with pathological conditions, particularly
obstructive sleep apnoea. However, IH is also increasingly used to enhance health and …

Enzyme replacement therapy (ERT) has paved the way for treating the somatic symptoms of
lysosomal storage diseases (LSDs), but the inability of intravenously administered enzymes …

The neurocognitive response following hypoxia has received special interest. However, it is
necessary to understand the impact of acute hypoxic exposure induced by simulated altitude …