Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome
BD Paul, MD Lemle, AL Komaroff… - Proceedings of the …, 2021 - National Acad Sciences
Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
Hydropersulfides inhibit lipid peroxidation and protect cells from ferroptosis
Hydropersulfides (RSSH) are believed to serve important roles in vivo, including as
scavengers of damaging oxidants and electrophiles. The α-effect makes RSSH not only …
scavengers of damaging oxidants and electrophiles. The α-effect makes RSSH not only …
[HTML][HTML] Supersulphides provide airway protection in viral and chronic lung diseases
T Matsunaga, H Sano, K Takita, M Morita… - Nature …, 2023 - nature.com
Supersulphides are inorganic and organic sulphides with sulphur catenation with diverse
physiological functions. Their synthesis is mainly mediated by mitochondrial cysteinyl-tRNA …
physiological functions. Their synthesis is mainly mediated by mitochondrial cysteinyl-tRNA …
Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation
D Giovinazzo, B Bursac, JI Sbodio… - Proceedings of the …, 2021 - National Acad Sciences
Alzheimer's disease (AD), the most common cause of dementia and neurodegeneration in
the elderly, is characterized by deterioration of memory and executive and motor functions …
the elderly, is characterized by deterioration of memory and executive and motor functions …
[HTML][HTML] HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron
Hypoxia is a hallmark of solid tumors that promotes cell growth, survival, and metastasis and
confers resistance to chemo and radiotherapies. Hypoxic responses are largely mediated by …
confers resistance to chemo and radiotherapies. Hypoxic responses are largely mediated by …
[HTML][HTML] Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics
Hydrogen sulfide (H 2 S) was once considered to have only toxic properties, until it was
discovered to be an endogenous signaling molecule. The effects of H 2 S are dose …
discovered to be an endogenous signaling molecule. The effects of H 2 S are dose …
NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications
Compounds with a nitrobenzoxadiazole (NBD) skeleton exhibit prominent useful properties
including environmental sensitivity, high reactivity toward amines and biothiols (including …
including environmental sensitivity, high reactivity toward amines and biothiols (including …
Highly Stable and Selective Sensing of Hydrogen Sulfide in Living Mouse Brain with NiN4 Single-Atom Catalyst-Based Galvanic Redox Potentiometry
C Pan, F Wu, J Mao, W Wu, G Zhao, W Ji… - Journal of the …, 2022 - ACS Publications
Hydrogen sulfide (H2S) is recognized as a gasotransmitter and multifunctional signaling
molecule in the central nervous system. Despite its essential neurofunctions, the chemical …
molecule in the central nervous system. Despite its essential neurofunctions, the chemical …
[HTML][HTML] Transsulfuration, minor player or crucial for cysteine homeostasis in cancer
Cysteine, a thiol-containing amino acid, is crucial for the synthesis of sulfur-containing
biomolecules that control multiple essential cellular activities. Altered cysteine metabolism …
biomolecules that control multiple essential cellular activities. Altered cysteine metabolism …