Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

The antitumor efficiency and clinical translation of traditional nanomedicines is mainly
restricted by low drug loading, complex preparation technology, and potential toxicity …

Cancer is a leading cause of death worldwide. Currently available therapies are inadequate
and spur demand for improved technologies. Rapid growth in nanotechnology towards the …

The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Peptide–drug conjugates (PDCs) represent an important class of therapeutic agents that
combine one or more drug molecules with a short peptide through a biodegradable linker …

Covalent modification of therapeutic compounds is a clinically proven strategy to devise
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …

Background Antibiotic resistance is one of the current threats to human health, forcing the
use of drugs that are more noxious, costlier, and with low efficiency. There are several …

Squalene (SQ) is a natural compound, a precursor of various hormones in animals and
sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional …

Lipid–drug conjugates (LDCs) are drug molecules that have been covalently modified with
lipids. The conjugation of lipids to drug molecules increases lipophilicity and also changes …

This opinion paper relates how nanoparticles were discovered in the seventies and how the
development of biodegradable materials and nanoparticle surface functionalization has …