Reprogrammed metabolism is a hallmark of colorectal cancer (CRC). CRC cells are geared
toward rapid proliferation, requiring nutrients and the removal of cellular waste in nutrient …

The small intestine displays marked anatomical and functional plasticity that includes
adaptive alterations in adult gut morphology, enteroendocrine cell profile and their hormone …

Long-term impacts of diet have been well studied; however, the immediate response of the
intestinal epithelium to a change in nutrients remains poorly understood. We use …

Endogenous small molecules play important roles in biological processes and are closely
related to the occurrence and development of many diseases. Profiling of spatial distribution …

There is evidence in humans that endocrine disrupting chemicals exposure, such as
bisphenol A (BPA), is tied to social behavior impacts when evaluated in early life stage …

Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …

Obesity results from a chronic excessive accumulation of adipose tissue due to a long-term
imbalance between energy intake and expenditure. Available epidemiological and clinical …

The regular overconsumption of energy‐dense foods (rich in lipids and sugars) results in
elevated intestinal nutrient absorption and consequently excessive accumulation of lipids in …

Enteroendocrine cells (EECs) are an essential interface between the gut and brain that
communicate signals about nutrients, pain, and even information from our microbiome …

Obesity is characterized by chronic low‐grade inflammation and is strongly associated with
multiple immunological diseases, including cancer and inflammatory diseases. Recent …