The role of lipid metabolism in COVID-19 virus infection and as a drug target

M Abu-Farha, TA Thanaraj, MG Qaddoumi… - International journal of …, 2020 - mdpi.com
The current Coronavirus disease 2019 or COVID-19 pandemic has infected over two million
people and resulted in the death of over one hundred thousand people at the time of writing …

A snapshot of the global race for vaccines targeting SARS-CoV-2 and the COVID-19 pandemic

CD Funk, C Laferrière, A Ardakani - Frontiers in pharmacology, 2020 - frontiersin.org
A novel coronavirus SARS-CoV-2 causing Coronavirus disease 2019 (COVID-19) has
entered the human population and has spread rapidly around the world in the first half of …

[HTML][HTML] Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double …

FC Zhu, XH Guan, YH Li, JY Huang, T Jiang, LH Hou… - The Lancet, 2020 - thelancet.com
Background This is the first randomised controlled trial for assessment of the
immunogenicity and safety of a candidate non-replicating adenovirus type-5 (Ad5)-vectored …

Advances in the design and development of SARS-CoV-2 vaccines

XL Peng, JSY Cheng, HL Gong, MD Yuan… - Military Medical …, 2021 - Springer
Since the end of 2019, coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. The RNA …

[HTML][HTML] Targets and strategies for vaccine development against SARS-CoV-2

JA Malik, AH Mulla, T Farooqi, FH Pottoo… - Biomedicine & …, 2021 - Elsevier
Abstract The SARS-CoV-2, previously called a novel coronavirus, that broke out in the
Wuhan city of China caused a significant number of morbidity and mortality in the world. It is …

Vacinas para COVID-19-o estado da arte

EJF Lima, AM Almeida, RÁ Kfouri - Revista Brasileira de Saúde …, 2021 - SciELO Brasil
As vacinas candidatas contra COVID-19 têm diversas composições, desde vacinas de vírus
inativados a várias de nova geração. Atualmente, cerca de 175 equipes de pesquisa em …

The impact of the COVID-19 “Infodemic” on drug-utilization behaviors: implications for pharmacovigilance

M Tuccori, I Convertino, S Ferraro, E Cappello… - Drug safety, 2020 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic that hit the world in 2020
triggered a massive dissemination of information (an “infodemic”) about the disease that was …

[HTML][HTML] Willingness to vaccinate against Covid-19: A qualitative study involving older adults from Southern Switzerland

M Fadda, LS Suggs, E Albanese - Vaccine: X, 2021 - Elsevier
Abstract Background The Covid-19 pandemic is causing unprecedented disruption and
suffering to people across the globe, with a disproportionate toll on the elderly. The …

Cellular immune responses to covid-19

HF Sewell, RM Agius, M Stewart, D Kendrick - Bmj, 2020 - bmj.com
B cells produce detectable antibodies in classes IgM, IgG, and IgA along with lesser
amounts of IgD and IgE. For SARS-CoV-2, the causative agent of covid-19, the focus is …

[HTML][HTML] Review of Covid-19 vaccine clinical trials-A puzzle with missing pieces

HF Kwok - International Journal of Biological Sciences, 2021 - ncbi.nlm.nih.gov
A year after the initial outbreak of Covid-19 pandemic, several Phase III clinical trials
investigating vaccine safety and efficacy have been published. These vaccine candidates …