Rho GTPases and signaling networks
L Van Aelst, C D'Souza-Schorey - Genes & development, 1997 - genesdev.cshlp.org
The Rho GTPases form a subgroup of the Ras superfamily of 20-to 30-kD GTP-binding
proteins that have been shown to regulate a wide spectrum of cellular functions. These …
proteins that have been shown to regulate a wide spectrum of cellular functions. These …
Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation
This review addresses the cellular and molecular mechanisms of cadherin-based tissue
morphogenesis. Tissue physiology is profoundly influenced by the distinctive organizations …
morphogenesis. Tissue physiology is profoundly influenced by the distinctive organizations …
A new secreted protein that binds to Wnt proteins and inhibits their activites
JC Hsieh, L Kodjabachian, ML Rebbert, A Rattner… - Nature, 1999 - nature.com
The Wnt proteins constitute a large family of extracellular signalling molecules that are found
throughout the animal kingdom and are important for a wide variety of normal and …
throughout the animal kingdom and are important for a wide variety of normal and …
Three-dimensional structure of the armadillo repeat region of β-catenin
AH Huber, WJ Nelson, WI Weis - Cell, 1997 - cell.com
Abstract β-catenin is essential for cadherin-based cell adhesion and Wnt/Wingless growth
factor signaling. In these roles, it binds to cadherins, Tcf-family transcription factors, and the …
factor signaling. In these roles, it binds to cadherins, Tcf-family transcription factors, and the …
[图书][B] The insect ovary: ultrastructure, previtellogenic growth and evolution
J Büning - 1994 - books.google.com
This book will give an overview of insect ovaries, showing the diversities and the common
traits in egg growth processes. The idea to write this book developed while looking at the …
traits in egg growth processes. The idea to write this book developed while looking at the …
β-Catenin mutations in cell lines established from human colorectal cancers
M Ilyas, IPM Tomlinson, A Rowan… - Proceedings of the …, 1997 - National Acad Sciences
β-catenin has functions as both an adhesion and a signaling molecule. Disruption of these
functions through mutations of the β-catenin gene (CTNNB1) may be important in the …
functions through mutations of the β-catenin gene (CTNNB1) may be important in the …
Germline Stem Cells Anchored by Adherens Junctions in the Drosophila Ovary Niches
X Song, CH Zhu, C Doan, T Xie - Science, 2002 - science.org
How stem cells are recruited to and maintained in their niches is crucial to understanding
their regulation and use in regenerative medicine. Here, we demonstrate that DE-cadherin …
their regulation and use in regenerative medicine. Here, we demonstrate that DE-cadherin …
Epithelial Cell Polarity and Cell Junctions in Drosophila
▪ Abstract The polarized architecture of epithelial cells and tissues is a fundamental
determinant of animal anatomy and physiology. Recent progress made in the genetic and …
determinant of animal anatomy and physiology. Recent progress made in the genetic and …
Overexpression of cadherins and underexpression of β-catenin inhibit dorsal mesoderm induction in early Xenopus embryos
J Heasman, A Crawford, K Goldstone… - Cell, 1994 - cell.com
The cadherin-catenin complex has an important role in cell-cell adhesion and may also
function in signaling pathways. We report that overexpression of three cadherin types in …
function in signaling pathways. We report that overexpression of three cadherin types in …
Signal transduction by the Wnt family of ligands
CT Dale - Biochemical Journal, 1998 - portlandpress.com
The Wnt genes encode a large family of secreted polypeptides that mediate cell-cell
communication in diverse developmental processes. The loss or inappropriate activation of …
communication in diverse developmental processes. The loss or inappropriate activation of …