Flavonoids such as baohuoside I and icaritin are the major active compounds in Epimedii
Folium (EF) and possess excellent therapeutic effects on various diseases. Encouragingly …

Nowadays, medicinal herbs and their phytochemicals have emerged as a great therapeutic
option for many disorders. However, poor bioavailability and selectivity might limit their …

Management of chronic wound has an immense impact on social and economic conditions
in the world. Healthcare costs, aging population, physical trauma, and comorbidities of …

Background: Autophagy regulates many cell functions related to cancer, ranging from cell
proliferation and angiogenesis to metabolism. Due to the close relationship between …

Naringenin (NAR), a flavonoid mainly found in citrus and grapefruits, has proven anti-cancer
activities. However, the poor water solubility and low bioavailability of NAR limits its use as a …

Icariin (ICA) is a kind of natural flavonoid compound monomer, which is derived from the
extract of dried stems and leaves of Epimedium. Modern pharmacological studies have …

The graph of drug resistance in cancer is reportedly increasing in terms of therapeutic
efficiency. As per the WHO reports, around 70% of death reported in low-and middle-income …

In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …

Thymoquinone (TQ), a natural polyphenol, has been associated with various
pharmacological responses; however, low bioavailability of TQ limits its clinical application …

Cancer remains the leading cause of death and rapidly evolving disease worldwide. The
understanding of disease pathophysiology has improved through advanced research …