Embryo implantation in humans is interstitial, meaning the entire conceptus embeds in the
endometrium before the placental trophoblast invades beyond the uterine mucosa into the …

The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …

Embryonic diapause–a period of embryonic suspension at the blastocyst stage–is a
fascinating phenomenon that occurs in over 130 species of mammals, ranging from bears …

Embryonic diapause (ED) is a temporary arrest of an embryo at the blastocyst stage when it
waits for the uterine receptivity signal to implant. ED used by over 100 species may also …

Human pluripotent stem cells (hPSCs; both embryonic and induced pluripotent) rapidly
proliferate in adherent culture to maintain their undifferentiated state. However, for mammals …

Embryonic diapause, the temporary suspension of development of the embryo, is a
fascinating reproductive strategy that has been frequently exploited across the animal …

Embryonic diapause is a maternally controlled phenomenon. The molecule controlling the
onset of the phenomenon is unknown. We demonstrated that overexpression of microRNA …

Diapause is a physiological adaptation to conditions that are unfavorable for growth or
reproduction. During diapause, animals become long-lived, stress-resistant …

Disseminated tumor cells (DTCs) are recognized as the seeds of metastasis. However,
metastatic lesions can become symptomatic years or decades after primary tumor removal …

The groundbreaking discovery that lower levels of insulin/IGF-1 signaling (IIS) can induce
lifespan extension was reported 24 years ago in the nematode Caenorhabditis elegans. In …