Nanotransducer-enabled deep-brain neuromodulation with NIR-II light

X Wu, F Yang, S Cai, K Pu, G Hong - ACS nano, 2023 - ACS Publications
The second near-infrared window (NIR-II window), which ranges from 1000 to 1700 nm in
wavelength, exhibits distinctive advantages of reduced light scattering and thus deep …

Near-infrared II fluorescence imaging

EL Schmidt, Z Ou, E Ximendes, H Cui… - Nature Reviews …, 2024 - nature.com
Fluorescence imaging in the second near-infrared (NIR-II) window enables deep-tissue
imaging with high resolution and improved contrast by taking advantage of the reduced light …

Activation of mechanoluminescent nanotransducers by focused ultrasound enables light delivery to deep-seated tissue in vivo

S Jiang, X Wu, F Yang, NJ Rommelfanger, G Hong - Nature Protocols, 2023 - nature.com
Light is used extensively in biological and medical research for optogenetic
neuromodulation, fluorescence imaging, photoactivatable gene editing and light-based …

Illuminating the brain: advances and perspectives in optoelectronics for neural activity monitoring and modulation

S Xu, M Momin, S Ahmed, A Hossain… - Advanced …, 2023 - Wiley Online Library
Optogenetic modulation of brain neural activity that combines optical and electrical modes in
a unitary neural system has recently gained robust momentum. Controlling illumination …

Optical neuromodulation at all scales: from nanomaterials to wireless optoelectronics and integrated systems

O Karatum, MJ Gwak, J Hyun, A Onal… - Chemical Society …, 2023 - pubs.rsc.org
Light-based neuromodulation systems offer exceptional spatiotemporal resolution combined
with the elimination of physical tether to communicate with neurons. Currently, optical …

Neural modulation with photothermally active nanomaterials

Y Wang, R Garg, D Cohen-Karni… - Nature Reviews …, 2023 - nature.com
Modulating neural electrophysiology with high precision is essential for understanding
neural communication and for the diagnosis and treatment of neural disorders. Photothermal …

Giant infrared bulk photovoltaic effect in tellurene for broad-spectrum neuromodulation

Z Wang, C Tan, M Peng, Y Yu, F Zhong… - Light: Science & …, 2024 - nature.com
Given the surpassing of the Shockley-Quiesser efficiency limit in conventional pn junction
photovoltaic effect, bulk photovoltaic effect (BPVE) has garnered significant research …

Principles and applications of sono-optogenetics

F Yang, SJ Kim, X Wu, H Cui, SK Hahn… - Advanced drug delivery …, 2023 - Elsevier
Optogenetics has revolutionized neuroscience research through its spatiotemporally precise
activation of specific neurons by illuminating light on opsin-expressing neurons. A long …

Hypothalamic warm-sensitive neurons require TRPC4 channel for detecting internal warmth and regulating body temperature in mice

Q Zhou, X Fu, J Xu, S Dong, C Liu, D Cheng, C Gao… - Neuron, 2023 - cell.com
Precise monitoring of internal temperature is vital for thermal homeostasis in mammals. For
decades, warm-sensitive neurons (WSNs) within the preoptic area (POA) were thought to …

Temperature-gated light-guiding hydrogel fiber for thermoregulation during optogenetic neuromodulation

G Chen, S Xu, Q Zhou, Y Zhang, Y Song, J Mi… - Advanced Fiber …, 2023 - Springer
With the rise of optogenetic manipulation of neurons, the effects of optogenetic heating on
temperature-sensitive physiological processes, and the damage to surrounding tissues have …