Antibiotic stewardship in the intensive care unit

CE Luyt, N Bréchot, JL Trouillet, J Chastre - Critical care, 2014 - Springer
The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …

[HTML][HTML] The diagnostic accuracy of procalcitonin for bacteraemia: a systematic review and meta-analysis

SH Hoeboer, PJ van der Geest, D Nieboer… - Clinical Microbiology …, 2015 - Elsevier
The diagnostic use of procalcitonin for bacterial infections remains a matter of debate. Most
studies have used ambiguous outcome measures such as sepsis instead of infection. We …

Biomarkers for sepsis

C Henriquez-Camacho, J Losa - BioMed research international, 2014 - Wiley Online Library
Bloodstream infections are a major concern because of high levels of antibiotic consumption
and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a …

A novel host-proteome signature for distinguishing between acute bacterial and viral infections

K Oved, A Cohen, O Boico, R Navon, T Friedman… - PloS one, 2015 - journals.plos.org
Bacterial and viral infections are often clinically indistinguishable, leading to inappropriate
patient management and antibiotic misuse. Bacterial-induced host proteins such as …

[PDF][PDF] Федеральные клинические рекомендации по оказания медицинской помощи детям с Желчекаменной болезнью

АА Баранов, ЛС Намазова-Баранова - МЗ РФ, Союз педиатров …, 2015 - astgmu.ru
Данные клинические рекомендации подготовлены совместно с Всероссийской
ассоциацией для больных муковисцидозом, рассмотрены и утверждены на заседании …

Sepsis biomarkers

M Prucha, G Bellingan, R Zazula - Clinica chimica acta, 2015 - Elsevier
Sepsis is the most frequent cause of death in non-coronary intensive care units (ICUs). In the
past 10 years, progress has been made in the early identification of septic patients and in …

Pseudomonas aeruginosa ventilator-associated pneumonia management

S Ramírez-Estrada, B Borgatta… - Infection and drug …, 2016 - Taylor & Francis
Ventilator-associated pneumonia is the most common infection in intensive care unit
patients associated with high morbidity rates and elevated economic costs; Pseudomonas …

[HTML][HTML] New role of biomarkers: mid-regional pro-adrenomedullin, the biomarker of organ failure

F Valenzuela-Sánchez… - Annals of …, 2016 - ncbi.nlm.nih.gov
Mid-regional pro-adrenomedullin (MR-proADM) has a good biomarker profile: its half-life is
several hours, and its plasma concentrations can be determined in clinical practice, it is …

Challenges and opportunities for antibiotic stewardship among preterm infants

S Mukhopadhyay, S Sengupta… - Archives of Disease in …, 2019 - fn.bmj.com
Antibiotic stewardship programmes aim to optimise antimicrobial use to prevent the
emergence of resistance species and protect patients from the side effects of unnecessary …

The use of procalcitonin (PCT) for diagnosis of sepsis in burn patients: a meta-analysis

L Cabral, V Afreixo, L Almeida, JA Paiva - PLoS One, 2016 - journals.plos.org
The continuous development of resuscitation techniques and intensive care reduced the
mortality rate induced by the initial shock in burn patients and, currently, infections …