The eukaryotic intestinal parasite Giardia intestinalis was first described in 1681, when
Antonie van Leeuwenhoek undertook a microscopic examination of his own diarrhoeal …

The secretory transport capacity of Giardia trophozoites is perfectly adapted to the changing
environment in the small intestine of the host and is able to deploy essential protective …

The presence of a nucleus and other membrane-bounded intracellular compartments is the
defining feature of eukaryotic cells. Endosymbiosis accounts for the origins of mitochondria …

Extracellular vesicles (EVs) facilitate intercellular communication and are considered a
promising therapeutic tool for the treatment of infectious diseases. These vesicles involve …

Giardia lamblia, also known as G. duodenalis and G. intestinalis, was first described in 1681
and is one of the most common intestinal protozoans throughout the world. In North America …

Giardia intestinalis parasites contain mitosomes, one of the simplest mitochondrion-related
organelles. Strategies to identify the functions of mitosomes have been limited mainly to …

The genome of the protozoan parasite Giardia lamblia is organized in two diploid nuclei,
which has so far precluded complete analysis of gene function. Here we use a previously …

The highly reduced protozoan parasite Giardia lamblia has minimal machinery for cellular
processes such as protein trafficking. Giardia trophozoites maintain diverse and regulated …

Background Mitochondria of opisthokonts undergo permanent fission and fusion throughout
the cell cycle. Here, we investigated the dynamics of the mitosomes, the simplest forms of …

Giardia lamblia is a flagellated protozoan enteroparasite transmitted as an environmentally
resistant cyst. Trophozoites attach to the small intestine of vertebrate hosts and proliferate by …