Since 2018, N-nitrosamine impurities have become a widespread concern in the global
regulatory landscape of pharmaceutical products. This concern arises due to their potential …

Many nitrosamines have been recognized to be carcinogenic for many decades. Despite the
fact that several nitrosamine precursors are frequently used in the manufacturing of …

In 2019, N-nitrosodimethylamine (NDMA) exceeding the maximum allowable intake (96
ng/day) was detected in metformin drug products in Singapore, and since then, many of the …

N-nitrosamines are genotoxic compounds which can be found as impurities in drug
substances and drug products used in the pharmaceutical industry. To date, several …

Nitrosamine compounds are classified as potential human carcinogens, the origin of these
impurities can be broadly classified in two categories, nitrosamine impurity found in drug …

Since December 2019, global batch recalls of metformin pharmaceutical products have
highlighted an urgent need to control N-nitrosodimethylamine (NDMA) contamination to …

Divalproex (DVS) is a popular drug widely used in various neurological and psychiatric
disorders. Commercially, it is a multisource-drug available in different generic equivalents …

The focus of current studies was to fabricate dose flexible printlets of dapsone (DDS) for
pediatric patients by selective laser sintering (SLS) 3D printing method, and evaluate its …

Abstract Between February 2020 and January 2022, the Food and Drug Administration
(FDA) recalled 281 metformin extended-release products due to the presence of N …

This study aims to find the effects of high (75%) and low (30%) humidity conditions and its
correlation with formulation composition on dissolution kinetics of lamotrigine (LMT) from …