The emerging impact of tumor budding in oral squamous cell carcinoma: main issues and clinical relevance of a new prognostic marker

L Togni, VCA Caponio, N Zerman, G Troiano… - Cancers, 2022 - mdpi.com
Simple Summary The results of tumor budding are an independent prognostic factor of
locoregional recurrences in many solid cancers, including colorectal, nasopharyngeal …

Emerging histopathologic markers in early‐stage oral tongue cancer: A systematic review and meta‐analysis

A Elseragy, IO Bello, A Wahab, RD Coletta… - Head & …, 2022 - Wiley Online Library
Although there are many histopathologic prognosticators, grading of early oral tongue
squamous cell carcinoma (OTSCC) is still based on morphological cell differentiation which …

Histopathology-based diagnosis of oral squamous cell carcinoma using deep learning

SY Yang, SH Li, JL Liu, XQ Sun… - Journal of Dental …, 2022 - journals.sagepub.com
Oral squamous cell carcinoma (OSCC) is prevalent around the world and is associated with
poor prognosis. OSCC is typically diagnosed from tissue biopsy sections by pathologists …

m6A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis

Y Cui, J Liu, L Liu, X Ma, Y Gui, H Liu, W Zhao - Cancer gene therapy, 2023 - nature.com
Abstract N6-methyladenosine (m6A) is an abundant nucleotide modification in mRNA, and
its emerging roles have been gradually identified. However, the potential function of m6A …

Relationship between tumor budding and partial epithelial–mesenchymal transition in head and neck cancer

K Okuyama, K Suzuki, S Yanamoto - Cancers, 2023 - mdpi.com
Simple Summary In this article, we outline updates on the current relevance of tumor
budding (TB) and partial epithelial–mesenchymal transition (p-EMT), both as a prognostic …

Comparison of the 7th and revised 8th UICC editions (2020) for oral squamous cell carcinoma: How does the reclassification impact staging and survival?

AK Struckmeier, P Eichhorn, A Agaimy, M Buchbender… - Virchows Archiv, 2024 - Springer
Since its introduction in 1968, the TNM (tumor, node, metastasis) classification established
by the International Union Against Cancer has provided a consistent framework for staging …

Predictive value of tumor budding in head and neck squamous cell carcinoma: an update

CM Chiesa-Estomba, L Thompson, A Agaimy, N Zidar… - Virchows Archiv, 2023 - Springer
Head and neck squamous cell carcinoma forms an anatomically and functionally complex
group of malignancies. The significant local aggressiveness and frequent regional relapses …

Cutaneous squamous cell carcinoma characterized by MALDI mass spectrometry imaging in combination with machine learning

LF Brorsen, JS McKenzie, MF Tullin, KMS Bendtsen… - Scientific Reports, 2024 - nature.com
Cutaneous squamous cell carcinoma (SCC) is an increasingly prevalent global health
concern. Current diagnostic and surgical methods are reliable, but they require considerable …

Tumor budding should be in oral cavity cancer reporting: A retrospective cohort study based on tumor microenvironment

A Tan, T Taskin - Cancers, 2023 - mdpi.com
Simple Summary In our study, which started with the hypothesis that there is a
histopathological marker that can be used to predict prognosis in oral squamous cell …

Exploring the combination of tumor‐stroma ratio, tumor‐infiltrating lymphocytes, and tumor budding with WHO histopathological grading on early‐stage oral squamous …

GVD Silva, E da Silva Dolens… - Journal of Oral …, 2023 - Wiley Online Library
Background While the relevance of the World Health Organization histopathological grading
system as a prognostic tool for oral squamous cell carcinoma has received many critics …