L Fachal, AM Dunning - Current opinion in genetics & development, 2015 - Elsevier
There are now more than 90 established breast cancer risk loci, with 57 new ones, revealed through genome-wide-association studies (GWAS) during the last two years. Established …
Q Cai, B Zhang, H Sung, SK Low, SS Kweon, W Lu… - Nature …, 2014 - nature.com
In a three-stage genome-wide association study among East Asian women including 22,780 cases and 24,181 controls, we identified 3 genetic loci newly associated with breast cancer …
By combining data from 160,500 individuals with breast cancer and 226,196 controls of Asian and European ancestry, we conducted genome-and transcriptome-wide association …
Y Kim, KY Yoo, MT Goodman - Asian Pacific Journal of Cancer …, 2015 - koreascience.kr
Although the incidence of breast cancer in Asia remains lower than in North America, Western Europe, and Oceania, rates have been increasing rapidly during the past few …
L Fejerman, N Ahmadiyeh, D Hu, S Huntsman… - Nature …, 2014 - nature.com
The genetic contributions to breast cancer development among Latinas are not well understood. Here we carry out a genome-wide association study of breast cancer in Latinas …
X Shu, J Long, Q Cai, SS Kweon, JY Choi… - Nature …, 2020 - nature.com
Known risk variants explain only a small proportion of breast cancer heritability, particularly in Asian women. To search for additional genetic susceptibility loci for breast cancer, here …
SL Park, I Cheng, CA Haiman - Cancer Epidemiology, Biomarkers & …, 2018 - AACR
Genome-wide association studies (GWAS) of cancer have identified more than 700 risk loci, of which approximately 80% were first discovered in European ancestry populations …
M Fareed, M Afzal - Egyptian Journal of Medical Human Genetics, 2013 - Elsevier
Genome-wide patterns of variation across individuals provide most powerful source of data for uncovering the history of migration, expansion, and adaptation of the human population …
The last 10 years witnessed an acceleration of our understanding of what genetic factors underpin the risk of breast cancer. Rare high-and moderate-penetrance variants such as …